A Novel CPAP Device With an Integrated Oxygen Concentrator for Low Resource Countries: In Vitro Validation and Usability Test in Field

IF 2.7 Q3 ENGINEERING, BIOMEDICAL

IEEE Open Journal of Engineering in Medicine and Biology Pub Date : 2024-06-12 DOI:10.1109/OJEMB.2024.3413574

Poletto Sofia;Zannin Emanuela;Ghilotti Emanuele;Putoto Giovanni;Ichto Jerry;Lochoro Peter;Obizu Moses;Okori Samuel;Corno Matteo;Dellacà Raffaele

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引用次数: 0

Abstract

Goal: To develop and validatea novel neonatal non-invasive respiratory support device prototype designed to operate in low-resource settings. Methods: The device integrates a blower-based ventilator and a portable oxygen concentrator. A novel control algorithm was designed to achieve the desired fraction of inspired oxygen (FiO ₂ ) while minimizing power consumption. The accuracy of the delivered FiO ₂ and the device power consumption were evaluated in vitro, and a formative usability test was conducted in a rural hospital in Uganda. Results: The agreement between the set and delivered FiO2 was high (limit of agreement:−5.6 ÷ 3.8%). For FiO2 below 60%, the control algorithm reduced the power drain by 50%. The device was also appreciated by intended users. Conclusion: The prototype proved effective in delivering oxygen-enriched continuous positive airway pressure in the absence of compressed air and oxygen, holding promise for a sustainable and effective implementation of neonatal respiratory support in low-resource settings.

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适用于资源匮乏国家的集成制氧机的新型 CPAP 设备：体外验证和现场可用性测试

目标：开发并验证一种新型新生儿无创呼吸支持设备原型，该设备专为在低资源环境下运行而设计。方法：该设备集成了鼓风机式呼吸机和便携式氧气浓缩器。设计了一种新颖的控制算法，以达到所需的吸入氧分数（FiO2），同时最大限度地降低功耗。在体外对输送 FiO2 的准确性和设备功耗进行了评估，并在乌干达的一家农村医院进行了形成性可用性测试。结果：设定的 FiO2 和输出的 FiO2 之间的一致性很高（一致性极限：-5.6 ÷ 3.8%）。当 FiO2 低于 60% 时，控制算法可将耗电量降低 50%。该设备还得到了预定用户的赞赏。结论事实证明，在没有压缩空气和氧气的情况下，该原型能有效提供富氧持续气道正压，有望在资源匮乏的环境中持续、有效地实施新生儿呼吸支持。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

IEEE Open Journal of Engineering in Medicine and Biology ENGINEERING, BIOMEDICAL-

CiteScore

9.50

自引率

3.40%

发文量

审稿时长

10 weeks

期刊介绍： The IEEE Open Journal of Engineering in Medicine and Biology (IEEE OJEMB) is dedicated to serving the community of innovators in medicine, technology, and the sciences, with the core goal of advancing the highest-quality interdisciplinary research between these disciplines. The journal firmly believes that the future of medicine depends on close collaboration between biology and technology, and that fostering interaction between these fields is an important way to advance key discoveries that can improve clinical care.IEEE OJEMB is a gold open access journal in which the authors retain the copyright to their papers and readers have free access to the full text and PDFs on the IEEE Xplore® Digital Library. However, authors are required to pay an article processing fee at the time their paper is accepted for publication, using to cover the cost of publication.