A comparison of foot fractures relative to other fragility fractures: a review and analysis of the American Orthopaedic Association's Own the Bone Database.

IF 4.2 2区 医学 Q1 ENDOCRINOLOGY & METABOLISM
Osteoporosis International Pub Date : 2024-10-01 Epub Date: 2024-06-18 DOI:10.1007/s00198-024-07153-x
Eric So, Christopher Juels, Ryan T Scott, Debra L Sietsema
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引用次数: 0

Abstract

Evidence regarding the risk factors and characteristics of those with foot fragility fractures compared to non-foot fragility fractures is limited. Foot fragility fracture patients are more likely to be younger female with a higher BMI. A foot fragility fracture is strongly predictive of a subsequent foot fragility fracture.

Purpose: Osteoporosis can clinically result in fragility fractures. Evidence regarding the risk factors and characteristics of foot fragility fractures compared to non-foot fragility fractures is limited. The American Orthopaedic Association's Own the Bone (OTB) is a bone health initiative with a substantial dataset. The purpose of this study was to examine and compare characteristics of patients presenting with isolated foot fragility fracture to those with a non-foot fragility fracture.

Methods: Between January 2009 and March of 2022, 58,001 fragility fractures occurred that were included in this cohort. A total of 750 patients had foot fragility fracture(s) and 57,251 patients had a non-foot fragility fracture that included shoulder, arm, elbow, forearm, wrist, spine, ribs, pelvis, hip, thigh, knee, tibia/fibula, and ankle. Demographics, fracture history, bone health factors, medication history, and medication use for each patient were reported in the OTB database. This data was utilized in our secondary cohort comparative analysis of characteristics and the risk of future fractures between foot fragility fracture and non-foot fragility fracture groups.

Results: Foot fragility fracture patients have a significantly higher probability to be younger (66.9 years old), female (91.5%), and have a higher BMI (28.3 kg/m2) compared to non-foot fragility fracture (p < 0.0001) patients. Patients with a foot fragility fracture are nine times (OR = 9.119, CI = 7.44-11.18, p < 0.001) more likely to have had a prior foot fragility fracture. Young, female patients with a prior foot fragility fracture are at higher risk of a future foot fragility fracture, and this risk increased as BMI increased.

Conclusions: Foot fragility fracture patients are more likely to be female and younger compared to patients with a non-foot fragility fracture. A foot fragility fracture is a sentinel event considering that a prior foot fragility fracture is strongly predictive of a subsequent foot fragility fracture.

Level of evidence: 3 (retrospective cohort).

Abstract Image

足部骨折与其他脆性骨折的比较:对美国骨科协会 Own the Bone 数据库的回顾与分析。
与非足部脆性骨折相比,有关足部脆性骨折患者的风险因素和特征的证据十分有限。足部脆性骨折患者多为年轻女性,体重指数(BMI)较高。目的:骨质疏松症可在临床上导致脆性骨折。与非足部脆性骨折相比,足部脆性骨折的风险因素和特征方面的证据十分有限。美国骨科协会的 "自己的骨头"(OTB)是一项骨健康计划,拥有大量的数据集。本研究的目的是检查并比较孤立性足部脆性骨折患者与非足部脆性骨折患者的特征:从 2009 年 1 月到 2022 年 3 月,共有 58,001 例脆性骨折患者被纳入该队列。共有 750 名患者患有足部脆性骨折,57251 名患者患有非足部脆性骨折,包括肩部、手臂、肘部、前臂、手腕、脊柱、肋骨、骨盆、髋部、大腿、膝部、胫骨/腓骨和踝关节。OTB 数据库报告了每位患者的人口统计学特征、骨折史、骨健康因素、用药史和用药情况。我们利用这些数据对足部脆性骨折组和非足部脆性骨折组的特征和未来骨折风险进行了二次队列比较分析:与非足部脆性骨折患者相比,足部脆性骨折患者年轻(66.9 岁)、女性(91.5%)和体重指数(28.3 kg/m2)较高的概率明显更高(P 结论:足部脆性骨折患者更容易发生骨折:与非足部脆性骨折患者相比,足部脆性骨折患者更可能是女性和年轻人。足部脆性骨折是一种哨点事件,因为之前的足部脆性骨折可强烈预测之后的足部脆性骨折:3(回顾性队列)。
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来源期刊
Osteoporosis International
Osteoporosis International 医学-内分泌学与代谢
CiteScore
8.10
自引率
10.00%
发文量
224
审稿时长
3 months
期刊介绍: An international multi-disciplinary journal which is a joint initiative between the International Osteoporosis Foundation and the National Osteoporosis Foundation of the USA, Osteoporosis International provides a forum for the communication and exchange of current ideas concerning the diagnosis, prevention, treatment and management of osteoporosis and other metabolic bone diseases. It publishes: original papers - reporting progress and results in all areas of osteoporosis and its related fields; review articles - reflecting the present state of knowledge in special areas of summarizing limited themes in which discussion has led to clearly defined conclusions; educational articles - giving information on the progress of a topic of particular interest; case reports - of uncommon or interesting presentations of the condition. While focusing on clinical research, the Journal will also accept submissions on more basic aspects of research, where they are considered by the editors to be relevant to the human disease spectrum.
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