Vitamin A deficiency in the MENA region: a 30-year analysis (1990–2019)

Saeid Safiri, Seyed Ehsan Mousavi, S. A. Nejadghaderi, Kimia Motlagh Asghari, N. Karamzad, M. Sullman, Ali-Asghar Kolahi, Morteza Abdollahi
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Abstract

Vitamin A deficiency (VAD) is a common micronutrient deficiency that imposes a substantial burden worldwide. This study examined the burden of VAD from 1990 to 2019 in the Middle East and North Africa (MENA) region by age, sex and sociodemographic index (SDI).The data were obtained from the Global Burden of Disease (GBD) 2019 database. We reported the prevalence, incidence, and years lived with disability (YLDs) that were attributable to VAD for the MENA region, along with its constituent countries.In 2019, the MENA region had 30.6 million prevalent cases of VAD, with an age-standardized prevalence rate of 5249.9 per 100,000 population. In addition, VAD was responsible for 62.2 thousand YLDs, with an age-standardized YLD rate of 10.2 per 100,000. The age-standardized prevalence [50.3% (−55.9 to −44.7)] and YLD [−49.3% (−55.3 to −43.1)] rates of VAD have significantly decreased since 1990. In 2019, the MENA region’s VAD-attributable YLD rate was below the global average for males and females across all age groups. Additionally, SDI was negatively associated the age-standardized YLD rate of VAD.This study underscores the necessity of frequently updating health data and developing guidelines and regulations to prevent, detect early, and effectively treat VAD in the MENA countries.
中东和北非地区的维生素 A 缺乏症:30 年分析(1990-2019 年)
维生素 A 缺乏症(VAD)是一种常见的微量营养素缺乏症,给全世界造成了巨大负担。本研究按年龄、性别和社会人口指数(SDI)分析了1990年至2019年中东和北非(MENA)地区维生素A缺乏症的负担。我们报告了中东和北非地区及其组成国家中可归因于 VAD 的流行率、发病率和残疾生活年数(YLDs)。2019 年,中东和北非地区有 3060 万例 VAD 流行病例,年龄标准化流行率为每 10 万人 5249.9 例。此外,VAD 还导致 6.22 万例 YLD,年龄标准化 YLD 患病率为每 10 万人 10.2 例。自 1990 年以来,VAD 的年龄标准化患病率 [50.3% (-55.9 to -44.7)]和 YLD [-49.3% (-55.3 to -43.1)]均显著下降。2019 年,中东和北非地区所有年龄组的男性和女性可归因于 VAD 的 YLD 比率均低于全球平均水平。此外,SDI 与 VAD 的年龄标准化 YLD 率呈负相关。这项研究强调,有必要经常更新健康数据并制定指导方针和法规,以便在中东和北非国家预防、早期发现并有效治疗 VAD。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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