Spectrum of Erythema Nodosum: A case series

Mohammed Baieas Chowdhury, M. Tonmoy, Rafiq Un Nabi Siam, Benojeer Akter, Khondoker Shoaib Hossain, Gourav Dey Sarker, Nandita Paul, Akhak Ahmed
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Abstract

Erythema nodosum (EN) is a common acute nodular septalpanniculitis, characterized by the sudden onset of erythematous, firm, solid, deep nodules or plaques painful on palpation and mainly localized on extensor surfaces of the legs. The changes resolve without skin ulcerations spontaneously within a few weeks (mean 2–8). Skin symptoms may be associated with arthralgia, fever, and weaknessThese nodules are characterized by a typical histological appearance regardless of the etiology, marked by acute inflammation of the dermo-hypodermic junction and interlobular septa of the hypodermic fat.Erythema nodosum can occur due to a vast number of underlying causes including but not limited to idiopathic, infectious, and a variety of noninfectious causes. Its occurrence is for the clinician a signal for a wider diagnosis and determination of the cause of occurrence of symptoms. Here we discuss 3 cases of EN of different etiologies and was treated accordingly. Bangladesh J Medicine 2024; Vol. 35, No. 2, Supplementation: 167
结节性红斑的谱系:病例系列
结节性红斑(EN)是一种常见的急性结节性隔肌炎,其特点是突然出现红斑、坚实、实性、深部结节或斑块,触诊时疼痛,主要发生在腿部伸肌表面。这些变化会在几周内(平均 2-8 周)自行消退,不会出现皮肤溃疡。无论病因如何,这些结节都具有典型的组织学外观,其特征是皮下脂肪的真皮-皮下交界处和小叶间隔膜的急性炎症。对于临床医生来说,结节性红斑的出现是一个信号,需要进行更广泛的诊断并确定症状出现的原因。在此,我们讨论了 3 例不同病因的 EN,并对其进行了相应的治疗。孟加拉国医学杂志 2024 年;第 35 卷,第 2 期,增刊:167
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