Axillary Web Syndrome in Newly Diagnosed Individuals after Surgery for Breast Cancer: Baseline Results from the AMBER Cohort Study

IF 0.9 4区医学 Q4 REHABILITATION

Physiotherapy Canada Pub Date : 2024-06-06 DOI:10.3138/ptc-2023-0088

Margaret L McNeely, K. S. Courneya, Mona M. Al Onazi, Qinggang Wang, Stephanie Bernard, Leanne Dickau, Jeff K. Vallance, S. Culos-Reed, Charles E Matthews, Lin Yang, C. Friedenreich

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引用次数: 0

Abstract

To examine potential associations between post-surgical axillary web syndrome (AWS) and demographic, medical, surgical, and health-related fitness variables in newly diagnosed individuals with breast cancer. Participants were recruited between 2012 and 2019. Objective measures of health-related fitness, body composition, shoulder range of motion (ROM) and function, and AWS were performed within 3 months of breast cancer surgery. AWS was identified in 243 (17.3%) participants and was associated with poorer shoulder ROM and function, and higher pain compared with women without AWS. Multivariable logistic regression analysis identified axillary lymph node dissection versus sentinel lymph node biopsy [OR = 3.97; 95% CI: 2.62, 6.03], mastectomy versus breast-conserving surgery [OR = 1.60, 95% CI: 1.17, 2.19], lower versus higher total percentage body fat [OR = 1.60; 95% CI: 1.10, 2.34], and earlier versus later time from surgery [OR: 1.56; 95% CI: 1.10, 2.23] as significantly associated with a higher odds of AWS. Higher cardiorespiratory fitness [OR =1.04; 95% CI: 1.01, 1.08] and university or higher education [OR = 1.47; 95% CI: 1.1, 2.00] were also associated with higher odds of presenting with AWS. Findings highlight the need for increased awareness of AWS to facilitate early detection and physiotherapy intervention in the early post-surgical period.

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乳腺癌手术后新确诊患者的腋窝网状结构综合征：AMBER 队列研究的基线结果

目的：研究新诊断的乳腺癌患者手术后腋窝网综合征（AWS）与人口统计学、医疗、手术和健康相关的体能变量之间的潜在关联。参与者招募时间为 2012 年至 2019 年。在乳腺癌手术后 3 个月内，对健康相关体能、身体成分、肩关节活动范围 (ROM) 和功能以及 AWS 进行了客观测量。在 243 名（17.3%）参与者中发现了 AWS，与没有 AWS 的女性相比，AWS 与较差的肩关节活动度和功能以及较高的疼痛有关。多变量逻辑回归分析发现，腋窝淋巴结清扫与前哨淋巴结活检[OR = 3.97; 95% CI: 2.62, 6.03]、乳房切除术与保乳手术[OR = 1.60, 95% CI: 1.17，2.19]、体脂总百分比较低与较高[OR = 1.60；95% CI：1.10，2.34]以及手术时间较早与较晚[OR：1.56；95% CI：1.10，2.23]与较高的 AWS 机率显著相关。较高的心肺功能[OR=1.04；95% CI：1.01，1.08]和大学或更高的教育程度[OR=1.47；95% CI：1.1，2.00]也与出现 AWS 的几率较高有关。研究结果突出表明，有必要提高人们对 AWS 的认识，以便在术后早期及早发现并进行物理治疗干预。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Physiotherapy Canada REHABILITATION-

CiteScore

1.90

自引率

20.00%

发文量

审稿时长

>12 weeks

期刊介绍： Physiotherapy Canada is the official, scholarly, refereed journal of the Canadian Physiotherapy Association (CPA), giving direction to excellence in clinical science and reasoning, knowledge translation, therapeutic skills and patient-centred care. Founded in 1923, Physiotherapy Canada meets the diverse needs of national and international readers and serves as a key repository of inquiries, evidence and advances in the practice of physiotherapy. Physiotherapy Canada publishes the results of qualitative and quantitative research including systematic reviews, meta analyses, meta syntheses, public/health policy research, clinical practice guidelines, and case reports. Key messages, clinical commentaries, brief reports and book reviews support knowledge translation to clinical practice. In addition to delivering authoritative, original scientific articles and reports of significant clinical studies, Physiotherapy Canada’s editorials and abstracts are presented in both English and French, expanding the journal’s reach nationally and internationally. Key messages form an integral part of each research article, providing a succinct summary for readers of all levels. This approach also allows readers to quickly get a feel for ‘what is already known’ and ‘what this study adds to’ the subject. Clinician’s commentaries for key articles assist in bridging research and practice by discussing the article’s impact at the clinical level. The journal also features special themed series which bring readers up to date research supporting evidence-informed practice. The Canadian Physiotherapy Association (CPA) is the national professional association representing almost 15,000 members distributed throughout all provinces and territories. CPA’s mission is to provide leadership and direction to the physiotherapy profession, foster excellence in practice, education and research, and promote high standards of health in Canada.