Clinical experience of outpatient treatment of bacterial skin infections in children

R. M. Zagrtdinova, Natalya V. Lyashenko, Rizilya N. Zagrtdinova, Tatyana P. Sergeeva, Tatyana A. Kobeleva, Dmitry D. Petrunin
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Abstract

Data regarding the role of cutaneous microbiome in physiological and pathological conditions, pharmacological properties of fusidic acid and its clinical use for the treatment of skin infections are presented in the article. Incidence of skin infections in children treated in children's city polyclinic №1 of Izhevsk city through 2019-2022 are analyzed. Outcomes of the treatment of these patients with topical fusidic acid preparations are presented. Due to high activity against typical cutaneous bacterial pathogens including MRSA strains of S. aureus, favorable safety profile and pharmacokinetic profile when topically applied along with low resistance of the key pathogens fusidic acid preparations are the first line treatment of primary and secondary pyodermas.
门诊治疗儿童皮肤细菌感染的临床经验
文章介绍了皮肤微生物群在生理和病理条件下的作用、夫西地酸的药理特性及其在治疗皮肤感染方面的临床应用。文章分析了伊热夫斯克市№1儿童市立综合医院在2019-2022年期间接受治疗的儿童皮肤感染发病率。文章介绍了使用局部夫西地酸制剂治疗这些患者的结果。由于夫西地酸制剂对典型的皮肤细菌病原体(包括金黄色葡萄球菌中的 MRSA 菌株)具有较高的活性,在局部使用时具有良好的安全性和药代动力学特征,而且主要病原体的耐药性较低,因此是治疗原发性和继发性脓皮病的一线药物。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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