DECIPHERING THE INTRICATE NETWORK OF POLY CYSTIC OVARIAN SYNDROME: A THOROUGH EXAMINATION OF HORMONAL AND DEMOGRAPHIC INFLUENCES

Abstract

One of the most prevalent hormonal disorders affecting women who are of reproductive age is PCOS, a serious public health concern. Insulin resistance is significantly more common together with hirsutism, polycystic ovaries, and oligo/anovulatory periods as typical symptoms and  other multitude of chronic health issues that impact quality of life are linked to PCOS.PCOS patient and control group (non-PCOS) hormonal profiles are compared in this study.TSH, FSH, LH, and AMH are measured in this research. The results clarify the hormonal irregularities and consequences of PCOS.The data shows that women with PCOS had significantly greater AMH than controls, with a sensitivity and specificity of 93%.AMH has an NPV and PPV of 83% and 97%, respectively.The majority of PCOS patients reported higher LH levels than the control group, which had 86% sensitivity and 88% specificity. The LH level is impacted by PCOS, as seen by the 95% of PPV and 69%, of NPV.The FSH levels of controls and PCOS patients are comparable. Since FSH levels are comparable, the primary hormonal imbalance in PCOS is probably elevated LH and AMH. PCOS patients showed higher TSH levels than the control group, which may cause thyroid issues since 43% of PCOS patients had elevated TSH.These findings illuminate PCOS hormone abnormalities. Furthermore, people with PCOS are more prone than the general population to suffering from the morbidity related to metabolic and cardiovascular diseases.Understanding the hormonal imbalances linked to PCOS makes future research easier, which is required to understand the etiology of PCOS and hormone-regulated PCOS treatment.