Risk Factors Associated with COVID-19 and Gastrointestinal Manifestations in Older Adult Patients

Anguiano-Velazquez Tabata Gabriela, Granados-Kraulles Jorge Arturo, Santiago-Sanchez Benita, Salcedo-Vargas Mauricio, Delgadillo-Urban Yerendira Margot, Herrerias-Colin Luis Angel, Huato-Andrade Cristhian, Chilpa-Garibay Angel Victor, Garcia-Gonzalez Angelica, Hernandez-Salinas Miguel, Lopez-Ramirez Eduardo, Gutierrez-Salcido Ana Luisa, Téllez-Guzman Irene Judith, Perez-Juarez Luis Daniel, Salmeron-Hilario Exequiel, Ruiz-Martinez Airym, Lopez-Hernandez Daniel
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Abstract

Aims: To establish the association of gastrointestinal symptoms and possible risk factors with COVID-19 in older adults. Study Design: An observational, cross-sectional, descriptive, retrospective study was designed using secondary sources, with a quantitative approach and non-probability convenience sampling. Place and Duration of Study: The study included a population of 312 records of individuals aged 18 and over with COVID-19. The population was divided into two groups: one consisting of individuals aged 18 to 59 and the other of individuals aged 60 and over. Methodology: Possible risk factors and gastrointestinal manifestations associated with COVID-19 in older adults were analysed using univariate and multivariate logistic regression models. Results: In older adults, the main gastrointestinal manifestation was diarrhea (OR=2.086, 95% CI 1.007-4.322, p=0.048). The risk of COVID-19 increased in older adults with type 2 diabetes (OR=2.053, 95% CI 1.149-3.671, p=0.015), hypertension (OR=2.34, 95% CI 1.191-4.596, p=0.014), and respiratory diseases (OR=8.049, 95% CI 1.913-33.868, p=0.004). Conclusion: In older adults, diarrhea is a symptom associated with COVID-19, and the primary risk factors were diabetes, hypertension, and respiratory diseases.
与 COVID-19 和老年患者胃肠道表现相关的风险因素
目的:确定老年人胃肠道症状及可能的风险因素与 COVID-19 的关联:研究设计:采用二手资料、定量方法和非概率便利抽样,设计了一项观察性、横断面、描述性、回顾性研究:研究对象包括 312 份 18 岁及以上的 COVID-19 患者记录。研究对象分为两组:一组是 18 至 59 岁的人,另一组是 60 岁及以上的人:方法:使用单变量和多变量逻辑回归模型分析了老年人中与 COVID-19 相关的可能风险因素和胃肠道表现:在老年人中,主要的胃肠道表现是腹泻(OR=2.086,95% CI 1.007-4.322,p=0.048)。患有 2 型糖尿病(OR=2.053,95% CI 1.149-3.671,P=0.015)、高血压(OR=2.34,95% CI 1.191-4.596,P=0.014)和呼吸系统疾病(OR=8.049,95% CI 1.913-33.868,P=0.004)的老年人患 COVID-19 的风险增加:在老年人中,腹泻是一种与 COVID-19 相关的症状,其主要风险因素是糖尿病、高血压和呼吸系统疾病。
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