Death due to multiple organ failure in a patient with severe COVID-19, AIDS, cardiovascular impairment, and previous lung infections

Francisco Medros Junior, Priscila Oliveira de Souza, Juliana Eymara Fernandes Barbosa de Paula, Mauricea Francisco da Silva Romero Gonzalez, Cristiane Gomes da Silva, D. F. Barreto-Vieira, Derick Mendes Bandeira
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Abstract

Objective: To report a case of SARS-CoV-2/HIV coinfection in a patient with a history of recent lung infections who had a cardiopulmonary arrest on the day of hospitalization for COVID-19 treatment, dying some days after multiple organ failure. Case detail: A 33-year-old immunosuppressed male patient (abandoning treatment for HIV) was admitted to the emergency department with respiratory symptoms and tested positive for SARS-CoV-2. During hospitalization, the patient had a cardiorespiratory arrest and presented a robust inflammatory profile, fungal infection, sepsis, metabolic acidosis, arterial hypertension, thrombosis, hemorrhage, and hepatic, muscular, and renal injury. Finally, he evolved with multiple organ failures, leading to death. Conclusion: Severe immunosuppression caused by HIV, associated with underlying cardiopulmonary diseases, contributes to lethal outcomes of COVID-19.
一名患有严重 COVID-19、艾滋病、心血管受损和既往肺部感染的患者因多器官衰竭而死亡
目的报告一例 SARS-CoV-2/HIV 合并感染病例,患者近期有肺部感染病史,在住院接受 COVID-19 治疗当天心肺功能骤停,多器官功能衰竭数日后死亡。病例详情:一名 33 岁的免疫抑制男性患者(放弃艾滋病毒治疗)因呼吸道症状被送入急诊科,经检测,SARS-CoV-2 病毒呈阳性。住院期间,患者心跳呼吸骤停,并出现了严重的炎症、真菌感染、败血症、代谢性酸中毒、动脉高血压、血栓形成、出血以及肝、肌肉和肾损伤。最后,他出现多器官衰竭,最终死亡。结论艾滋病病毒引起的严重免疫抑制,加上潜在的心肺疾病,是导致 COVID-19 死亡的原因。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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