IgA Vasculitis Secondary to Enterococcus Faecalis Cardiac Device Infective Endocarditis; A Case Report, Discussion of the Literature and Protocol for Assessment of Inflammatory Skin Lesions in Emergency Medicine

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Abstract

A 68-year-old Caucasian male presented to the emergency department for administration of IV ceftriaxone post discharge for Enterococcus faecalis Cardiac Device Infective Endocarditis (CDIE). The patient reported a rash on his legs which had been present for many weeks. On examination the rash a revealed non-blanching purpuric rash resembling leukocytoclastic vasculitis. Biopsy and serology performed in our rural emergency department confirmed IgA vasculitis (IgAV). The patient had no systemic features to suggest IgA nephritis, or other systemic disease and the rash resolved with no additional treatment. A discussion of the differential diagnoses in this case highlights the importance of opportunistic biopsy and vasculitis serology in the rural emergency department setting and recommends screening for underlying cancer given the close association of IgAV with malignancy. The importance of emergency department protocols for assessment of skin lesions suggestive of an underlying systemic disease is also discussed.
继发于粪肠球菌心脏设备感染性心内膜炎的 IgA 血管炎;病例报告、文献讨论和急诊医学中炎症性皮肤病变的评估规程
一名 68 岁的白种男性因患粪肠球菌性心脏装置感染性心内膜炎 (CDIE) 出院后到急诊科接受头孢曲松静脉注射。患者称其腿部出现皮疹已有数周。对皮疹进行检查后发现,皮疹为非淤斑性紫癜,类似白细胞凝集性血管炎。我们在农村急诊科进行的活检和血清学检查证实了 IgA 血管炎(IgAV)。该患者没有任何全身特征,表明其患有 IgA 肾炎或其他全身性疾病,而且无需额外治疗,皮疹即可消退。对该病例鉴别诊断的讨论强调了在农村急诊科环境中进行机会性活检和血管炎血清学检查的重要性,并建议筛查潜在的癌症,因为 IgAV 与恶性肿瘤密切相关。此外,还讨论了急诊科对提示潜在系统性疾病的皮肤病变进行评估的重要性。
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