{"title":"Application of expired Febuxostat drug as an effective corrosion inhibitor for steel in acidic medium: Experimental and theoretical studies","authors":"Mohit Jaiswal, Akhil Saxena, Jasdeep Kaur","doi":"10.1016/j.cdc.2024.101149","DOIUrl":null,"url":null,"abstract":"<div><p>This work investigates the possibility of using expired Febuxostat, a drug mainly used to treat gout, as a corrosion inhibitor for steel in solutions containing Hydrochloric acid (HCl), which is an unusual but potentially successful approach. The goal of this research is to recycle pharmaceutical waste for useful purposes while also meeting the requirement for sustainable and economical corrosion mitigation techniques. The study includes various analytical techniques, like SEM, weight loss, electrochemical techniques, and density functional theory (DFT) to evaluate the efficacy of expired febuxostat as a corrosion inhibitor for steel in 0.5 M HCl solution. The EIS and PDP curve results showed a direct correlation between the concentration of Febuxostat and the inhibition efficiency. The active center of the electrode surface is blocked by the drug molecules, which reduces the corrosion mechanism. The data from the Langmuir adsorption isotherm validates a physiochemical process. Moreover, SEM investigations show that steel has a smoother surface. The adsorption behavior of Febuxostat molecules on the steel surface is investigated, providing insight into the chemical mechanisms underlying the inhibitory effect.</p></div>","PeriodicalId":269,"journal":{"name":"Chemical Data Collections","volume":"52 ","pages":"Article 101149"},"PeriodicalIF":2.2180,"publicationDate":"2024-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chemical Data Collections","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2405830024000375","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Chemistry","Score":null,"Total":0}
引用次数: 0
Abstract
This work investigates the possibility of using expired Febuxostat, a drug mainly used to treat gout, as a corrosion inhibitor for steel in solutions containing Hydrochloric acid (HCl), which is an unusual but potentially successful approach. The goal of this research is to recycle pharmaceutical waste for useful purposes while also meeting the requirement for sustainable and economical corrosion mitigation techniques. The study includes various analytical techniques, like SEM, weight loss, electrochemical techniques, and density functional theory (DFT) to evaluate the efficacy of expired febuxostat as a corrosion inhibitor for steel in 0.5 M HCl solution. The EIS and PDP curve results showed a direct correlation between the concentration of Febuxostat and the inhibition efficiency. The active center of the electrode surface is blocked by the drug molecules, which reduces the corrosion mechanism. The data from the Langmuir adsorption isotherm validates a physiochemical process. Moreover, SEM investigations show that steel has a smoother surface. The adsorption behavior of Febuxostat molecules on the steel surface is investigated, providing insight into the chemical mechanisms underlying the inhibitory effect.
期刊介绍:
Chemical Data Collections (CDC) provides a publication outlet for the increasing need to make research material and data easy to share and re-use. Publication of research data with CDC will allow scientists to: -Make their data easy to find and access -Benefit from the fast publication process -Contribute to proper data citation and attribution -Publish their intermediate and null/negative results -Receive recognition for the work that does not fit traditional article format. The research data will be published as ''data articles'' that support fast and easy submission and quick peer-review processes. Data articles introduced by CDC are short self-contained publications about research materials and data. They must provide the scientific context of the described work and contain the following elements: a title, list of authors (plus affiliations), abstract, keywords, graphical abstract, metadata table, main text and at least three references. The journal welcomes submissions focusing on (but not limited to) the following categories of research output: spectral data, syntheses, crystallographic data, computational simulations, molecular dynamics and models, physicochemical data, etc.