Current Advances in the Management of Nonurothelial Subtypes of Bladder Cancer.

Q1 Medicine
Evangelia Vlachou, Burles Avner Johnson, Ezra Baraban, Rosa Nadal, Jean Hoffman-Censits
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引用次数: 0

Abstract

Urothelial cancer (UC) is the most common histology seen in bladder tumors. The 2022 WHO classification of urinary tract tumors includes a list of less common subtypes (formerly known as variants) for invasive UC which are considered high-grade tumors. This review summarizes the most recent advances in the management of selected nonurothelial subtypes of bladder cancer: squamous cell carcinoma, small cell carcinoma, sarcomatoid urothelial carcinoma, micropapillary carcinoma, plasmacytoid carcinoma, adenocarcinoma, and urachal carcinoma. The role of neoadjuvant and adjuvant chemotherapy has not been well characterized for most of these histologies, and prospective data are extremely limited. Participation in clinical trials is recommended in advanced disease.

非神经上皮亚型膀胱癌治疗的最新进展》(Current Advances in the Management of Non-urothelial Subtypes of Bladder Cancer)。
尿路上皮癌(UC)是膀胱肿瘤中最常见的组织学类型。2022 年世卫组织泌尿系统肿瘤分类中列出了较少见的浸润性 UC 亚型(以前称为变异型),这些亚型被认为是高级别肿瘤。本综述总结了治疗部分非尿路上皮亚型膀胱癌的最新进展:鳞状细胞癌、小细胞癌、肉瘤样尿路上皮癌、微乳头状癌、浆细胞癌、腺癌和尿道癌。新辅助化疗和辅助化疗在大多数组织学中的作用尚不明确,前瞻性数据也极为有限。建议晚期患者参加临床试验。
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期刊介绍: The Ed Book is a National Library of Medicine–indexed collection of articles written by ASCO Annual Meeting faculty and invited leaders in oncology. Ed Book was launched in 1985 to highlight standards of care and inspire future therapeutic possibilities in oncology. Published annually, each volume highlights the most compelling research and developments across the multidisciplinary fields of oncology and serves as an enduring scholarly resource for all members of the cancer care team long after the Meeting concludes. These articles address issues in the following areas, among others: Immuno-oncology, Surgical, radiation, and medical oncology, Clinical informatics and quality of care, Global health, Survivorship.
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