La fuerza de presión inicial como factor predictivo del riesgo de amputación en pacientes con pie diabético

IF 2.3 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL
E. Imre , E. Imre , S. Ozturk
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Abstract

Background

We aimed to analyze the prognostic significance of handgrip strength as predictor of lower extremity amputation at 1 year follow up in patients with type 2 diabetes.

Methods

We evaluated 526 patients with type 2 diabetes between August 2020 and June 2022. We collected from the electronic medical records demographic variables, laboratory data and history of amputation. The handgrip strength was assessed using a handheld Smedley digital dynamometer following the NHANES Muscle Strenght/Grip Test Procedure. Low handgrip strength was defined for women as less than 16 kg and for men less than 27 kg. Outcome variable was major or minor lower extremity amputation.

Results

A total of 205 patients with complete data entered the study. Patients mean age was 59 years old, 37% were women and the mean diabetes disease duration was 14 years. Seventy-seven (37%) patients suffered from lower extremity mputations (26 major and 51 minor amputations). After controlling for age, gender, presence of peripheral artery disease, body mass index and white cell counts as confounder variables, patients with low handgrip had an increased risk for amputations (Odds Ratio 2.17; 95% confidence interval: 1.09-4.32; P < .001).

Conclusion

Low handgrip stregth is an independent prognostic marker for lower limb amputation at one year in patients with diabetes.

预测糖尿病足患者截肢风险的初始压力力
背景我们旨在分析手握力作为 2 型糖尿病患者随访 1 年后下肢截肢预测指标的预后意义。我们从电子病历中收集了人口统计学变量、实验室数据和截肢史。我们按照 NHANES 肌肉力量/握力测试程序,使用手持式 Smedley 数字测力计对患者的手握力进行了评估。女性的低握力定义为低于 16 千克,男性的低握力定义为低于 27 千克。结果变量为主要或次要下肢截肢。患者平均年龄为 59 岁,37% 为女性,平均糖尿病病程为 14 年。77例(37%)患者患有下肢截肢(26例大腿截肢,51例小腿截肢)。在控制了年龄、性别、是否患有外周动脉疾病、体重指数和白细胞计数等混杂变量后,低握力患者截肢的风险增加(Odds Ratio 2.17;95% 置信区间:1.09-4.32;P < .001)。
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来源期刊
Revista clinica espanola
Revista clinica espanola 医学-医学:内科
CiteScore
4.40
自引率
6.90%
发文量
73
审稿时长
28 days
期刊介绍: Revista Clínica Española published its first issue in 1940 and is the body of expression of the Spanish Society of Internal Medicine (SEMI). The journal fully endorses the goals of updating knowledge and facilitating the acquisition of key developments in internal medicine applied to clinical practice. Revista Clínica Española is subject to a thorough double blind review of the received articles written in Spanish or English. Nine issues are published each year, including mostly originals, reviews and consensus documents.
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