Photoredox-Catalyzed Hydrogenation of Alkenes Assisted by in situ Generated PPh3(OH) Radical and Acetic Acid

IF 4.6 1区化学 Q1 CHEMISTRY, ORGANIC

Organic Chemistry Frontiers Pub Date : 2024-06-07 DOI:10.1039/d4qo00661e

Zhen-Zhen Xie, Yu Zheng, Zi-Hao Liao, Chu-Ping Yuan, Ming-Zhi Li, Ke-yi Deng, Haoyue Xiang, Kai Chen, Hua Yang

引用次数: 0

Abstract

Herein, a practical, mild and convenient strategy was disclosed for the hydrogenation of alkenes under photocatalytic conditions through HAT/protonation process. A combination of experimental and computational studies suggested water was activated by a phosphine radical cation to generate the critical intermediate PR3(OH) radical, which acted as a “free” hydrogen atom to faciliate the initial HAT process.

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原位生成的 PPh3(OH)自由基和乙酸辅助的光氧化催化烯烃氢化反应

本文揭示了一种在光催化条件下通过 HAT/质子化过程进行烯烃氢化的实用、温和、便捷的策略。实验和计算研究表明，水被膦自由基阳离子激活，生成临界中间体 PR3(OH)自由基，该自由基作为 "自由 "氢原子促进了最初的 HAT 过程。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Organic Chemistry Frontiers CHEMISTRY, ORGANIC-

CiteScore

7.90

自引率

11.10%

发文量

686

审稿时长

1 months

期刊介绍： Organic Chemistry Frontiers is an esteemed journal that publishes high-quality research across the field of organic chemistry. It places a significant emphasis on studies that contribute substantially to the field by introducing new or significantly improved protocols and methodologies. The journal covers a wide array of topics which include, but are not limited to, organic synthesis, the development of synthetic methodologies, catalysis, natural products, functional organic materials, supramolecular and macromolecular chemistry, as well as physical and computational organic chemistry.