Jing Keng, Sue-Kei Lee, Sze-Huey Sang, Kai-Bin Liew, S. Teo, Wan Mastura Shaik Mohamed Mossadeq, Sek-Chuen Chow, G. Akowuah, Siew-Keah Lee, C. Mai, Yik-Ling Chew
{"title":"Cassia alata and Its Phytochemicals: A Promising Natural Strategy in Wound Recovery","authors":"Jing Keng, Sue-Kei Lee, Sze-Huey Sang, Kai-Bin Liew, S. Teo, Wan Mastura Shaik Mohamed Mossadeq, Sek-Chuen Chow, G. Akowuah, Siew-Keah Lee, C. Mai, Yik-Ling Chew","doi":"10.3390/sci6020034","DOIUrl":null,"url":null,"abstract":"Cassia alata, a traditional herb with a global presence, is renowned for its anti-inflammatory, antibacterial, and antifungal properties, making it a go-to remedy for skin ailments. While it has demonstrated wound healing capabilities in both in vitro and in vivo studies, the precise mechanisms remain elusive. This review aims to highlight its key phytochemicals, their effects, and the mechanism of action. The compounds that have been reviewed and discussed include kaempferol, apigenin, quercetin, rhein, and rutin. These polyphenols play important roles in normal and impaired wound healing processes, encompassing hemostasis, inflammation, proliferation, and tissue remodeling.","PeriodicalId":510703,"journal":{"name":"Sci","volume":"59 7","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Sci","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3390/sci6020034","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Cassia alata, a traditional herb with a global presence, is renowned for its anti-inflammatory, antibacterial, and antifungal properties, making it a go-to remedy for skin ailments. While it has demonstrated wound healing capabilities in both in vitro and in vivo studies, the precise mechanisms remain elusive. This review aims to highlight its key phytochemicals, their effects, and the mechanism of action. The compounds that have been reviewed and discussed include kaempferol, apigenin, quercetin, rhein, and rutin. These polyphenols play important roles in normal and impaired wound healing processes, encompassing hemostasis, inflammation, proliferation, and tissue remodeling.