Engineering cancer’s end: An interdisciplinary approach to confront the complexities of cancer

IF 48.8 1区医学 Q1 CELL BIOLOGY

Cancer Cell Pub Date : 2024-06-06 DOI:10.1016/j.ccell.2024.05.017

Elsa R. Flores, W. Gregory Sawyer

引用次数: 0

Abstract

Cancer engineering is an interdisciplinary approach that promises to confront the complexities of cancer and accelerate transformative discoveries by integrating innovative fields across engineering and the physical sciences with a focus on cancer. We offer a conceptual framework for the hallmarks of cancer engineering, integrating 12 fields: system dynamics; imaging, radiation, and spectroscopy; robotics and controls; solid mechanics; fluid mechanics; chemistry and nanomaterials; mathematics and simulation; cellular and protein engineering; kinetics and thermodynamics; materials science; manufacturing and biofabrication; and microsystems.

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工程学终结癌症：应对癌症复杂性的跨学科方法

癌症工程学是一种跨学科方法，有望通过整合工程学和物理科学的创新领域来应对癌症的复杂性并加速变革性发现，重点关注癌症。我们为癌症工程的特点提供了一个概念框架，整合了 12 个领域：系统动力学；成像、辐射和光谱学；机器人和控制；固体力学；流体力学；化学和纳米材料；数学和模拟；细胞和蛋白质工程；动力学和热力学；材料科学；制造和生物制造；以及微系统。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cancer Cell 医学-肿瘤学

CiteScore

55.20

自引率

1.20%

发文量

179

审稿时长

4-8 weeks

期刊介绍： Cancer Cell is a journal that focuses on promoting major advances in cancer research and oncology. The primary criteria for considering manuscripts are as follows: Major advances: Manuscripts should provide significant advancements in answering important questions related to naturally occurring cancers. Translational research: The journal welcomes translational research, which involves the application of basic scientific findings to human health and clinical practice. Clinical investigations: Cancer Cell is interested in publishing clinical investigations that contribute to establishing new paradigms in the treatment, diagnosis, or prevention of cancers. Insights into cancer biology: The journal values clinical investigations that provide important insights into cancer biology beyond what has been revealed by preclinical studies. Mechanism-based proof-of-principle studies: Cancer Cell encourages the publication of mechanism-based proof-of-principle clinical studies, which demonstrate the feasibility of a specific therapeutic approach or diagnostic test.