Multifaceted simulation: Finite volume and finite element modeling of blood flow in multiple stenosed arteries

IF 1.8 4区 物理与天体物理 Q3 PHYSICS, APPLIED
Jamil Abbas Haider, Shahbaz Ahmad, Khaled A. Gepreel, R. A. Rahman
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引用次数: 0

Abstract

Cardiovascular illnesses are a primary global health concern because they are frequently brought on by arterial stenosis. The complicated hemodynamics of blood flow via elliptically shaped arteries with numerous stenotic lesions along their top and bottom walls are examined in this paper. Carreau fluid model is used with Navier–Stokes equations in this study. The complete comparative study is done by using the Finite Element and Finite Volume Methods. This study uses commercial software to examine blood flow velocity, pressure and temperature distributions under various physiological situations at Reynolds number 30. Our results illuminate the interaction between flow dynamics, stenosis characteristics, and arterial geometry. The novelty of the work is to investigate how stenosis size, shape, and location affect pressure gradients, and flow disturbances. These observations provide helpful direction for understanding disease progression, designing treatments, and possibly new stent designs. The future direction of this research may involve further exploration of the interplay between hemodynamics and arterial stenosis by incorporating advanced computational models. Additionally, studies focusing on in vivo validation and clinical applications could enhance the translational impact of the findings. Collaborations between researchers, clinicians, and engineers may pave the way for personalized treatment strategies and innovations in cardiovascular care based on a deeper understanding of the intricate dynamics within diseased arteries.

多方面模拟:多支狭窄动脉血流的有限体积和有限元建模
心血管疾病是全球关注的首要健康问题,因为它们通常是由动脉狭窄引起的。本文研究了血液流经椭圆形动脉时的复杂血流动力学,这些动脉的上下壁上有许多狭窄病变。本研究使用了 Carreau 流体模型和 Navier-Stokes 方程。使用有限元法和有限体积法进行了完整的比较研究。本研究使用商业软件在雷诺数为 30 的条件下研究了各种生理情况下的血流速度、压力和温度分布。我们的研究结果阐明了血流动力学、狭窄特征和动脉几何形状之间的相互作用。这项工作的新颖之处在于研究了狭窄的大小、形状和位置如何影响压力梯度和流动干扰。这些观察结果为了解疾病进展、设计治疗方法以及可能的新型支架设计提供了有益的方向。这项研究的未来方向可能包括通过结合先进的计算模型,进一步探索血液动力学与动脉狭窄之间的相互作用。此外,以体内验证和临床应用为重点的研究可以增强研究结果的转化影响。研究人员、临床医生和工程师之间的合作可能会为个性化治疗策略铺平道路,并在深入了解病变动脉内部复杂动态的基础上实现心血管护理的创新。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Modern Physics Letters B
Modern Physics Letters B 物理-物理:凝聚态物理
CiteScore
3.70
自引率
10.50%
发文量
235
审稿时长
5.9 months
期刊介绍: MPLB opens a channel for the fast circulation of important and useful research findings in Condensed Matter Physics, Statistical Physics, as well as Atomic, Molecular and Optical Physics. A strong emphasis is placed on topics of current interest, such as cold atoms and molecules, new topological materials and phases, and novel low-dimensional materials. The journal also contains a Brief Reviews section with the purpose of publishing short reports on the latest experimental findings and urgent new theoretical developments.
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