Lemierre’s syndrome: A clinician's dilemma – A case report

Abstract

Lemierre's syndrome (LS) is a life-threatening, rare condition that starts with an oropharyngeal infection leading to internal jugular vein septic thrombophlebitis and potentially severe systemic complications, highlighting the need for prompt recognition and treatment by healthcare professionals. We present a case of LS in a 37-year-old male who initially presented with a sore throat, cough, and high-grade fever. A diagnostic workup revealed a positive blood culture with Fusobacterium necrophorum, and an ultrasound examination demonstrated internal jugular vein thrombophlebitis, confirming the diagnosis of LS. Treatment commenced with oral antibiotics planned for 6 weeks, alongside oral anticoagulation scheduled for 12 weeks. Our case underscores the need for vigilance and multidisciplinary collaboration in managing LS, highlighting the importance of prompt recognition, targeted therapies, and ongoing research to optimize outcomes and enhance diagnosis and management.