Adverse neonatal outcome associated with maternal tuberculosis in a public tertiary centre: a retrospective cohort study.

Q3 Medicine

Medical Journal of Malaysia Pub Date : 2024-05-01

Z Zurina, M A Nunis, A F A Abdulla, M Osman, N Zakaria

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引用次数: 0

Abstract

Introduction: The aim of this study was to evaluate a group of infants born to women with tuberculosis (TB) during pregnancy to determine the neonatal morbidities and its outcomes associated with tuberculosis in pregnancy.

Materials and methods: Data from January 2007 to December 2021 was collected for analysis as part of a retrospective cohort study. This study was conducted in a tertiary public hospital in Malaysia, Hospital Sultan Idris Shah (HSIS). Cases were identified from the hospital's bacille Calmette-Guerin (BCG) vaccination notification forms and merged with records from the neonatal intensive care unit's census. Controls were infants born to mothers unaffected by TB within the same hospital and year as the index case (1:4 ratio). Descriptive statistics and logistic regression were used to analyse the data. The main outcome measures were the risk of congenital tuberculosis, premature birth, low birth weight, small for gestational age and low APGAR score.

Results: Data from January 2007 to December 2021 was collected for analysis as part of a retrospective cohort study. This study was conducted in a tertiary public hospital in Malaysia, Hospital Sultan Idris Shah (HSIS). Cases were identified from the hospital's bacille Calmette-Guerin (BCG) vaccination notification forms and merged with records from the neonatal intensive care unit's census. Controls were infants born to mothers unaffected by TB within the same hospital and year as the index case (1:4 ratio). Descriptive statistics and logistic regression were used to analyse the data. The main outcome measures were the risk of congenital tuberculosis, premature birth, low birth weight, small for gestational age and low APGAR score.

本刊更多论文

公立三级医院中与产妇结核病相关的新生儿不良预后：一项回顾性队列研究。

导言：本研究的目的是对妊娠期患结核病（TB）的妇女所生的一组婴儿进行评估，以确定与妊娠期结核病相关的新生儿发病率及其结果：作为回顾性队列研究的一部分，收集了 2007 年 1 月至 2021 年 12 月的数据进行分析。这项研究在马来西亚的一家三级公立医院--苏丹伊德里斯沙医院（Hospital Sultan Idris Shah，HSIS）进行。病例从医院的卡介苗（Bacille Calmette-Guerin，BCG）接种通知单中确定，并与新生儿重症监护室的普查记录合并。对照组为与指标病例同院同年出生、母亲未受结核病影响的婴儿（1:4）。数据分析采用了描述性统计和逻辑回归法。主要结果指标为先天性肺结核、早产、低出生体重、胎龄小和低APGAR评分的风险：作为回顾性队列研究的一部分，我们收集了 2007 年 1 月至 2021 年 12 月的数据进行分析。这项研究在马来西亚的一家三级公立医院--苏丹伊德里斯沙医院（Hospital Sultan Idris Shah，HSIS）进行。病例从医院的卡介苗（Bacille Calmette-Guerin，BCG）接种通知单中确定，并与新生儿重症监护室的普查记录合并。对照组为与指标病例同院同年出生、母亲未受结核病影响的婴儿（1:4）。数据分析采用了描述性统计和逻辑回归法。主要结果指标为先天性肺结核、早产、低出生体重、胎龄小和低 APGAR 评分的风险。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Medical Journal of Malaysia Medicine-Medicine (all)

CiteScore

1.20

自引率

0.00%

发文量

165

期刊介绍： Published since 1890 this journal originated as the Journal of the Straits Medical Association. With the formation of the Malaysian Medical Association (MMA), the Journal became the official organ, supervised by an editorial board. Some of the early Hon. Editors were Mr. H.M. McGladdery (1960 - 1964), Dr. A.A. Sandosham (1965 - 1977), Prof. Paul C.Y. Chen (1977 - 1987). It is a scientific journal, published quarterly and can be found in medical libraries in many parts of the world. The Journal also enjoys the status of being listed in the Index Medicus, the internationally accepted reference index of medical journals. The editorial columns often reflect the Association''s views and attitudes towards medical problems in the country. The MJM aims to be a peer reviewed scientific journal of the highest quality. We want to ensure that whatever data is published is true and any opinion expressed important to medical science. We believe being Malaysian is our unique niche; our priority will be for scientific knowledge about diseases found in Malaysia and for the practice of medicine in Malaysia. The MJM will archive knowledge about the changing pattern of human diseases and our endeavours to overcome them. It will also document how medicine develops as a profession in the nation. We will communicate and co-operate with other scientific journals in Malaysia. We seek articles that are of educational value to doctors. We will consider all unsolicited articles submitted to the journal and will commission distinguished Malaysians to write relevant review articles. We want to help doctors make better decisions and be good at judging the value of scientific data. We want to help doctors write better, to be articulate and precise.