3D Printing for the Development of Palatal Defect Prosthetics.

Christian Calderon, Autreen Golzar, Stephen Marcott, Kyle Gifford, Sandy Napel, Dominik Fleischmann, Fred M Baik, Thomas F Osborne, Andrey Finegersh, Davud Sirjani
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Abstract

Background: Three-dimensional (3D) printing has emerged as a promising new technology for the development of surgical prosthetics. Research in orthopedic surgery has demonstrated that using 3D printed customized prosthetics results in more precise implant placements and better patient outcomes. However, there has been little research on implementing customized 3D printed prosthetics in otolaryngology. The program sought to determine whether computed tomography (CT) serves as feasible templates to construct 3D printed palatal obturator prosthetics for defects in patients who have been treated for head and neck cancers.

Observations: A retrospective review of patients with palatal defects was conducted and identified 1 patient with high quality CTs compatible with 3D modeling. CTs of the patient's craniofacial anatomy were used to develop a 3D model and a Formlabs 3B+ printer printed the palatal prosthetic. We successfully developed and produced an individualized prosthetic using CTs from a veteran with head and neck deformities caused by cancer treatment who was previously treated at the Veterans Affairs Palo Alto Health Care System. This project was successful in printing patient-specific implants using CT reproductions of the patient's craniofacial anatomy, particularly of the palate. The program was a proof of concept and the implant we created was not used on the patient.

Conclusions: Customized 3D printed implants may allow otolaryngologists to enhance the performance and efficiency of surgeries and better rehabilitate and reconstruct craniofacial deformities to restore appearance and function to patients. Additional research will strive to enhance the therapeutic potential of these prosthetics to serve as low-cost, patient-specific implants.

3D 打印技术用于开发腭部缺损修复体。
背景:三维(3D)打印技术已成为开发外科假体的一项前景广阔的新技术。骨科手术方面的研究表明,使用三维打印定制假体可以使植入物的位置更精确,患者的治疗效果更好。然而,在耳鼻喉科中使用定制 3D 打印假体的研究却很少。该计划旨在确定计算机断层扫描(CT)是否可作为可行的模板,为接受过头颈部癌症治疗的患者构建3D打印腭钝器假体:我们对患有腭部缺损的患者进行了回顾性检查,发现 1 名患者的高质量 CT 与 3D 建模相匹配。患者颅面部解剖结构的 CT 图像被用于开发三维模型,Formlabs 3B+ 打印机打印出了腭假体。我们利用一名曾在退伍军人事务帕洛阿尔托医疗保健系统接受治疗的因癌症治疗导致头颈部畸形的退伍军人的 CT 图像,成功开发并制作了个性化假体。该项目成功地利用患者颅面部解剖结构(尤其是腭部)的 CT 复制品打印出了患者专用的假体。该项目只是概念验证,我们制作的植入体并未用于患者:定制的三维打印植入物可以让耳鼻喉科医生提高手术的效果和效率,更好地康复和重建颅面畸形,恢复患者的外观和功能。其他研究将努力提高这些假体的治疗潜力,使其成为低成本、针对特定患者的植入体。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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