{"title":"A Novel Clay Based Electrocatalyst for Lactate Detection in Saliva and Blood Samples during Exercise in Athletes","authors":"Hao Liu, Najmeh Zare","doi":"10.1007/s11244-024-01967-z","DOIUrl":null,"url":null,"abstract":"<p>In this research, a new non-enzymatic amperometric sensor has been developed for the determination of lactate based on a sepiolite@Pt electrocatalyst. The uniform dispersion of small-sized platinum nanoparticles (NPs) leads to optimized electron transfer kinetics, thereby low lactate detection ability of the modified carbon paste electrode (CPE). The innovative sensing platform demonstrates a linear response to lactate concentrations ranging from 10 to 1100 µM. By using a signal-to-noise ratio of 3σ, a detection limit of 2 µM was established. Moreover, the precise analysis of lactate in human fluids suggests that the proposed method is a highly specific tool for lactate monitoring. Notably, the sensor’s capabilities were extended to include the measurement of lactate concentrations in saliva samples obtained during sport practice. The proposed method offers a cost-effective and efficient means of lactate monitoring, enabling rapid analysis times and streamlined clinical testing procedures.</p>","PeriodicalId":801,"journal":{"name":"Topics in Catalysis","volume":"129 1","pages":""},"PeriodicalIF":2.8000,"publicationDate":"2024-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Topics in Catalysis","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1007/s11244-024-01967-z","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, APPLIED","Score":null,"Total":0}
引用次数: 0
Abstract
In this research, a new non-enzymatic amperometric sensor has been developed for the determination of lactate based on a sepiolite@Pt electrocatalyst. The uniform dispersion of small-sized platinum nanoparticles (NPs) leads to optimized electron transfer kinetics, thereby low lactate detection ability of the modified carbon paste electrode (CPE). The innovative sensing platform demonstrates a linear response to lactate concentrations ranging from 10 to 1100 µM. By using a signal-to-noise ratio of 3σ, a detection limit of 2 µM was established. Moreover, the precise analysis of lactate in human fluids suggests that the proposed method is a highly specific tool for lactate monitoring. Notably, the sensor’s capabilities were extended to include the measurement of lactate concentrations in saliva samples obtained during sport practice. The proposed method offers a cost-effective and efficient means of lactate monitoring, enabling rapid analysis times and streamlined clinical testing procedures.
期刊介绍:
Topics in Catalysis publishes topical collections in all fields of catalysis which are composed only of invited articles from leading authors. The journal documents today’s emerging and critical trends in all branches of catalysis. Each themed issue is organized by renowned Guest Editors in collaboration with the Editors-in-Chief. Proposals for new topics are welcome and should be submitted directly to the Editors-in-Chief.
The publication of individual uninvited original research articles can be sent to our sister journal Catalysis Letters. This journal aims for rapid publication of high-impact original research articles in all fields of both applied and theoretical catalysis, including heterogeneous, homogeneous and biocatalysis.