Woodfordia fruticosa is a well-known medicinal plant traditionally used for various treatment methods. Green synthesis of silver nanocomposite with woodfordia flower extract is well-investigated. However, the therapeutic potential of Woodfordia fruticosa leaf extract silver nanoparticles against various diseases has yet to be investigated.
RESULTS
Silver nanoparticles synthesized from Woodfordia fruticosa leaf extract (Wf-AgNPs) showed UV spectral peaks at 450 nm. Transmission electron microscope (TEM) images, ranging from 20 to 50 nm, confirm the nanosynthesis. The average particle size of 39.63 nm with a zeta potential distribution value 17.0 was observed. Fourier transform infrared peaks ranging from 2942to 669 cm−1 confirm the amines, amides, carboxylic, aldehyde, alkane, phenolic and aliphatic bromo compounds involved in the synthesis of AgNPs. Wf-AgNPs showed higher antioxidant activity compared to the ascorbic acid and BHT. The phenolic and flavonoid content was 141.66 ± 8.50 mg GAE/100 g dry weight and 191.66 ± 5.6 mg quercetin equivalent/100 g dry weight, respectively. Wf-AgNPs showed a strong inverse relationship between the dose and viability of the cancer cells. The antibacterial properties of Wf-AgNPs were confirmed through the bacteria's SEM images. Increased wound healing potential, re-epithelization and elevation of the tensile strength of the infected skin tissue were observed after applying synthesized Wf-AgNPs.
期刊介绍:
Journal of Chemical Technology and Biotechnology(JCTB) is an international, inter-disciplinary peer-reviewed journal concerned with the application of scientific discoveries and advancements in chemical and biological technology that aim towards economically and environmentally sustainable industrial processes.