Implant reconstruction after mastectomy–A review and summary of current literature

Q3 Medicine
Thomas Kidd, Gerard Mccabe, Joanna Tait, Dhananjay Kulkarni
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引用次数: 0

Abstract

Introduction

The landscape of breast reconstruction has changed significantly with a shift in focus to include the restoration of a patient's quality of life after cancer. Reconstructive options can be divided into alloplastic (implant based) and autologous (tissue based). This paper aims to provide a current educational summary regarding implant-based reconstruction after breast cancer surgery and review the current literature.

Method

A review of the literature was conducted utilising standard PRISMA flowchart. Databases searched included Pubmed, EMBASE, and MEDLINE.

Results

Current practice is explored within the text, including types of implants, indications, and surgical approaches. Heterogenous cohorts, surgical technique variation, and selection bias can make comparison of the literature challenging. The major evidence reviews of implant-based reconstruction topics are discussed including, ADM use, radiotherapy, and complications. Despite the benefits of autologous reconstruction, implant-based techniques still represent a significant proportion of reconstructive breast procedures. However, implant-reconstruction is not without its risks and limitations and, with such variety in practice, there remains a lack of high-quality evidence guiding practice. Most importantly, patients need to be counselled about the pros and cons of each choice, particularly with the increasing utilisation of radiotherapy post-reconstruction. Ultimately, the patient and surgeon should reach a decision in full knowledge of the risks and potential outcomes.

Conclusions

Further research is required into implant-based reconstructive therapy, which will allow a greater consensus for management and a pathway for both surgeons and patients.

乳房切除术后的植入物重建--当前文献综述与总结
导言:随着癌症患者生活质量的恢复,乳房重建的重点发生了重大变化。重建方法可分为异体(以植入物为基础)和自体(以组织为基础)两种。本文旨在提供一份有关乳腺癌术后植入物重建的教育摘要,并对现有文献进行回顾。方法采用标准的 PRISMA 流程图对文献进行回顾。结果文中探讨了当前的做法,包括植入物的类型、适应症和手术方法。不同的队列、手术技术的差异和选择偏差会使文献比较具有挑战性。文中讨论了基于植入物的重建的主要证据回顾,包括 ADM 的使用、放射治疗和并发症。尽管自体重建有很多优点,但植入物重建技术在乳房重建手术中仍占很大比例。然而,植入物再造并非没有风险和局限性,而且由于实践中的多样性,仍然缺乏高质量的证据来指导实践。最重要的是,患者需要了解每种选择的利弊,尤其是在乳房再造术后越来越多地使用放射治疗的情况下。最终,患者和外科医生应该在充分了解风险和潜在结果的基础上做出决定。结论需要进一步研究以植入物为基础的重建疗法,这将为外科医生和患者的管理和治疗路径达成更多共识。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
4.30
自引率
0.00%
发文量
148
审稿时长
56 days
期刊介绍: Cancer Treatment and Research Communications is an international peer-reviewed publication dedicated to providing comprehensive basic, translational, and clinical oncology research. The journal is devoted to articles on detection, diagnosis, prevention, policy, and treatment of cancer and provides a global forum for the nurturing and development of future generations of oncology scientists. Cancer Treatment and Research Communications publishes comprehensive reviews and original studies describing various aspects of basic through clinical research of all tumor types. The journal also accepts clinical studies in oncology, with an emphasis on prospective early phase clinical trials. Specific areas of interest include basic, translational, and clinical research and mechanistic approaches; cancer biology; molecular carcinogenesis; genetics and genomics; stem cell and developmental biology; immunology; molecular and cellular oncology; systems biology; drug sensitivity and resistance; gene and antisense therapy; pathology, markers, and prognostic indicators; chemoprevention strategies; multimodality therapy; cancer policy; and integration of various approaches. Our mission is to be the premier source of relevant information through promoting excellence in research and facilitating the timely translation of that science to health care and clinical practice.
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