CLINICOPATHOLOGICAL FACTORS AND THEIR PROGNOSTIC IMPORTANCE IN EWING SARCOMA: AN INSTITUTIONAL STUDY

Abstract

Background: Ewing sarcoma family of tumors are aggressive tumors with small round cell morphology constituting 6% to 8% of primary bone tumors occuring in children and young adults. Aims: Study aims to identify the differences in the clinicopathological features and their prognostic importance in patients with skeletal and extraskeletal Ewing sarcoma Methodology: A retrospective hospital based study was carried out in the department of pathology from January 2015 to June 2023 after getting approval from institutional committee. Clinic pathological data of Ewing sarcoma cases were collected from hospital records and analyzed. Results: our study included 37 cases of Ewings sarcoma. Out of which maximum were skeletal and showed male predominance. Skeletal Ewings were seen more in at bones and extraskeletal in thigh. Maximum number of tumors were seen in the age group below 20years and were of size more than 5cms. Metastasis was seen in maximum number of extraskeletal ewings, with tumor size larger than 5cms and in patients with age group less than 20 years. Conclusion: Extra skeletal Ewing sarcoma, male sex, age less than 20 years, size more than 5cms were associated with worse prognosis.