[Acute heart failure (AHF)].

IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL
Stefanie Boll, Eleonora Lupi, Thomas Wolters, Tobias Höfflinghaus, Mattia Arrigo
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引用次数: 0

Abstract

Introduction: Acute heart failure (AHF) is a frequent cause for emergency consultations, leads to long hospital stays and is characterized by high mortality and rehospitalization rates, with the first months after hospitalization having the highest risk («vulnerable phase»). The clinical presentation is usually characterized by fluid accumulation. Over the last three decades, few advances have been achieved in the treatment of AHF, as most studies with diuretics or vasodilators failed to show positive effects in terms of mortality and rehospitalization rates. In this context, the treatment of AHF must have an integrative approach, consisting of rapid correction of systemic congestion on the one hand, and specific therapies for the precipitating factors, the underlying cardiac pathology, and non-cardiac comorbidities on the other. Recently, it has been shown that a rapid and intensive up-titration of oral heart failure medical therapy during and immediately after hospitalization can improve the prognosis during the vulnerable phase after AHF. In this article, the principles of optimization and personalization of diuretic therapy and oral heart failure medication during hospitalization and the early outpatient phase after AHF are discussed.

[急性心力衰竭(AHF)]。
简介急性心力衰竭(AHF)是急诊的常见病,会导致长期住院,死亡率和再住院率都很高,住院后的头几个月风险最高("脆弱期")。临床表现通常以积液为特征。在过去的三十年里,由于大多数使用利尿剂或血管扩张剂的研究都未能在死亡率和再住院率方面显示出积极的效果,因此在治疗急性肾功能衰竭方面几乎没有取得任何进展。在这种情况下,AHF 的治疗必须采用综合方法,一方面要迅速纠正全身充血,另一方面要针对诱发因素、潜在的心脏病理和非心脏合并症采取特殊疗法。最近的研究表明,在住院期间和住院后立即进行快速、强化的心衰口服药物治疗,可以改善急性心力衰竭后脆弱期的预后。本文将讨论 AHF 后住院期间和早期门诊阶段利尿剂治疗和心衰口服药物的优化和个性化原则。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
THERAPEUTISCHE UMSCHAU
THERAPEUTISCHE UMSCHAU MEDICINE, GENERAL & INTERNAL-
CiteScore
0.50
自引率
0.00%
发文量
75
期刊介绍: Monat für Monat ein aktuelles Thema der praktischen Medizin - als Sammlung ein hochaktuelles Nachschlagewerk.
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