Polycythemia Vera Masked by Megaloblastic Anemia.

Q3 Medicine
The gulf journal of oncology Pub Date : 2024-05-01
M Loukhnati, K Khalil, F E Lahlimi, I Tazi
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引用次数: 0

Abstract

Polycythemia vera (PV) is a chronic myeloproliferative disorder characterized by uncontrolled red blood cell production. Megaloblastic anemia is caused by deficiency of cobalamin (vitamin B12) and/or folate (vitamin B9). While B12 deficiency may be caused by insufficient dietary intake or impairment of its utilization, its association with PV is described without exact knowledge of the physiopathology. We herein report the occurrence of megaloblastic anemia due to Vitamin B12 deficiency in an 85-year-old North African woman patient with PV. This case highlights this atypical presentation of PV and challenges that comes with it causing the delay of diagnosis and the complexity of its diagnosis and treatment. Keywords: megaloblastic anemia, polycythemia vera, association, case report.

被巨幼红细胞性贫血掩盖的多发性红细胞症。
多发性红细胞症(PV)是一种慢性骨髓增生性疾病,其特点是红细胞生成失控。巨幼红细胞性贫血是由于缺乏钴胺素(维生素 B12)和/或叶酸(维生素 B9)引起的。B12 缺乏可能是由于膳食摄入不足或其利用障碍引起的,但在描述其与巨幼红细胞症的关系时,并未确切了解其生理病理。我们在此报告了一名 85 岁的北非女性红斑狼疮患者因缺乏维生素 B12 而导致巨幼红细胞性贫血的病例。本病例强调了巨幼红细胞症的非典型表现,以及随之而来的诊断延迟和诊断与治疗的复杂性所带来的挑战。关键词:巨幼细胞性贫血;多发性红细胞症;关联;病例报告。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
The gulf journal of oncology
The gulf journal of oncology Medicine-Medicine (all)
CiteScore
0.90
自引率
0.00%
发文量
37
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