Pre-operative carbohydrate drink in pediatric spine fusion: randomized control trial.

IF 1.6 Q3 CLINICAL NEUROLOGY
Spine deformity Pub Date : 2024-09-01 Epub Date: 2024-05-20 DOI:10.1007/s43390-024-00890-3
Jennifer M Bauer, Michael Trask, Grace Coughlin, Maya Gopalan, Apeksha Gupta, Burt Yaszay, Scott Yang, Eliot Grigg
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引用次数: 0

Abstract

Purpose: As rapid discharge protocols for pediatric spine fusion shorten stays, gastrointestinal (GI) complications are uncovered and cause delays in discharge. A pre-operative carbohydrate (CHO) drink has been shown to improve perioperative GI symptoms and functional return but has not been examined in pediatric spine patients. We aimed to determine if a preoperative CHO drink is safe in pediatric spine fusion patients, and if it improves their comfort scores and return of bowel function.

Methods: We prospectively randomized ASA-1 and -2 pediatric spine fusion patients to either a pre-anesthesia carbohydrate drink 2 h prior to surgery or to a control group (standard 8 h NPO), blinded to surgical team. We documented time to return to flatus, bowel movement, GI symptoms, and comfort scores for 72 h post-operatively or until discharge.

Results: 62 patients were randomized. There was no significant differences between the groups' pre-operative characteristics, surgical details, nor post-operative morphine dose equivalents, except for EBL (405 cc control, 340 cc CHO drink, p = 0.044). There were no perioperative complications related to ingestion of the CHO drink. CHO group had a positive trend for earlier return of flatus (21% vs. 3% return at 12 h), and comfort scores for anxiety and abdominal pain, but no statistically significant differences. There was no difference in length of stay or time to first bowel movement.

Conclusion: There were no complications related to ingestion of a CHO drink 2 h prior to pediatric spinal fusion surgery. Further studies are needed to develop a study blinded to the participants with larger sample size. Level of evidence I.

小儿脊柱融合术术前碳水化合物饮料:随机对照试验。
目的:随着小儿脊柱融合术的快速出院方案缩短了住院时间,胃肠道(GI)并发症也随之出现,并导致出院延迟。有研究表明,术前碳水化合物(CHO)饮料可改善围手术期胃肠道症状和功能恢复,但尚未对小儿脊柱患者进行过研究。我们的目的是确定术前碳水化合物饮料对小儿脊柱融合术患者是否安全,以及是否能改善他们的舒适度评分和肠道功能恢复:我们对ASA-1和-2级小儿脊柱融合术患者进行了前瞻性随机分组,让他们在手术前2小时饮用麻醉前碳水化合物饮料或对照组(标准8小时NPO),并对手术团队设置了盲法。我们记录了术后 72 小时或出院前恢复排便、肠蠕动、消化道症状和舒适度评分的时间:结果:62 名患者被随机分组。除 EBL(对照组 405 毫升,CHO 饮料组 340 毫升,P = 0.044)外,各组的术前特征、手术细节和术后吗啡剂量当量均无明显差异。围手术期没有出现与摄入 CHO 饮料有关的并发症。CHO 组胀气恢复时间更早(12 小时内胀气恢复率为 21% 对 3%),焦虑和腹痛舒适度评分呈正向趋势,但差异无统计学意义。住院时间和首次排便时间没有差异:结论:小儿脊柱融合手术前 2 小时摄入 CHO 饮料不会引起并发症。需要进一步开展研究,对参与者进行盲法研究,并扩大样本量。证据等级 I。
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来源期刊
CiteScore
3.20
自引率
18.80%
发文量
167
期刊介绍: Spine Deformity the official journal of the?Scoliosis Research Society is a peer-refereed publication to disseminate knowledge on basic science and clinical research into the?etiology?biomechanics?treatment?methods and outcomes of all types of?spinal deformities. The international members of the Editorial Board provide a worldwide perspective for the journal's area of interest.The?journal?will enhance the mission of the Society which is to foster the optimal care of all patients with?spine?deformities worldwide. Articles published in?Spine Deformity?are Medline indexed in PubMed.? The journal publishes original articles in the form of clinical and basic research. Spine Deformity will only publish studies that have institutional review board (IRB) or similar ethics committee approval for human and animal studies and have strictly observed these guidelines. The minimum follow-up period for follow-up clinical studies is 24 months.
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