The paucity of high-level evidence for therapy in pediatric cardiology.

IF 0.9 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS
Annals of Pediatric Cardiology Pub Date : 2023-09-01 Epub Date: 2024-04-01 DOI:10.4103/apc.apc_120_23
Emily Littman, Diana Hsiao, Kanekal S Gautham
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引用次数: 0

Abstract

Introduction: Clinical practice should be based on the highest quality of evidence available. Therefore, we aimed to classify publications in the field of pediatric cardiology in the year 2021 based on the level of scientific evidence.

Materials and methods: A PubMed search was performed to identify pediatric cardiology articles published in the calendar year 2021. The abstract or manuscript of each study was reviewed. Each study was categorized as high, medium, or low level of evidence based on the study design. Disease investigated, treatment studied, and country of publication were recorded. Randomized control trials (RCTs) in similar fields of neonatology and adult cardiology were identified for comparison. Descriptive statistics were performed on the level of evidence, type of disease, country of publication, and therapeutic intervention.

Results: In 2021, 731 studies were identified. A decrease in prevalence for the level of evidence as a function of low, medium, and high was found (50.1%, 44.2%, and 5.8%, respectively). A low level of evidence studies was the majority for all types of cardiac disease identified, including acquired heart disease, arrhythmias, congenital heart disease, and heart failure, and for treatment modalities, including circulatory support, defibrillator, percutaneous intervention, medicine, and surgery. In a subgroup analysis, most high-level evidence studies were from the USA (31%), followed by China (26.2%) and India (14.3%). Comparing RCTs, 21 RCTs were identified in pediatric cardiology compared to 178 in neonatology and 413 in adult ischemic heart disease.

Conclusions: There is a great need for the conduct of studies that offer a high level of evidence in the discipline of pediatric cardiology.

儿科心脏病学治疗缺乏高水平的证据。
导言:临床实践应以现有的最高质量的证据为基础。因此,我们旨在根据科学证据的水平对 2021 年发表在儿科心脏病学领域的文章进行分类:我们在 PubMed 上进行了搜索,以确定 2021 年发表的儿科心脏病学文章。对每项研究的摘要或手稿进行审查。根据研究设计,将每项研究分为高、中、低证据级别。研究的疾病、治疗方法和发表国家均有记录。此外,还确定了新生儿科和成人心脏科类似领域的随机对照试验(RCT),以便进行比较。对证据水平、疾病类型、发表国和治疗干预进行了描述性统计:结果:2021 年,共确定了 731 项研究。发现证据级别为低、中、高的流行率有所下降(分别为 50.1%、44.2% 和 5.8%)。低证据水平的研究在所有类型的心脏病(包括后天性心脏病、心律失常、先天性心脏病和心力衰竭)和治疗方式(包括循环支持、除颤器、经皮介入、药物和手术)中占大多数。在分组分析中,大多数高级别证据研究来自美国(31%),其次是中国(26.2%)和印度(14.3%)。比较研究性试验,发现儿科心脏病学有21项研究性试验,而新生儿科有178项,成人缺血性心脏病有413项:结论:在儿科心脏病学领域,亟需开展能提供高水平证据的研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Annals of Pediatric Cardiology
Annals of Pediatric Cardiology CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
1.40
自引率
14.30%
发文量
51
审稿时长
23 weeks
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