UPLC-Q-TOF-MSE Based Profiling of the Chemical Composition of Different Parts of Tetrastigma hemsleyanum

Natural Product Communications Pub Date : 2024-05-01 DOI:10.1177/1934578x241239494

Lingxia Peng, Feng Yin, Xiuyue Li, Jiahao Fang, Hongju Li, Xinhan Xu, Pengguo Xia, Zongsuo Liang, Xiaodan Zhang

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Abstract

Objectives: The differences in chemical constituents in different parts of Tetrastigma hemsleyanum were analyzed. Methods: The contents of total phenols, total flavonoids, and polysaccharides in methanol extracts from different parts of T. hemsleyanum in Zhejiang were determined, and the chemical components of different parts of T. hemsleyanum were collected by ultra-performance liquid chromatography-tandem quadrupole-time-of-flight mass spectrometry. The differential index components of different parts of T. hemsleyanum were identified and analyzed by accurate mass-to-charge ratio of primary mass spectrometry and fragment ion of secondary mass spectrometry with reference spectrum and software database search and related literature reports. Results: A total of 20 components were identified, including 13 identified in root tubers, 7 in fibrous roots and 8 in leaves, and the structural cleavage of its compounds was analyzed. Conclusion: It provides a possibility and theoretical basis for the future use of the whole plant of T. hemsleyanum as medicine.

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基于 UPLC-Q-TOF-MSE 的 Tetrastigma hemsleyanum 不同部位化学成分分析

研究目的分析 Tetrastigma hemsleyanum 不同部位化学成分的差异。方法采用超高效液相色谱-串联四极杆飞行时间质谱法测定了浙江浙贝母不同部位甲醇提取物中总酚、总黄酮和多糖的含量，并收集了浙贝母不同部位的化学成分。采用一级质谱的精确质荷比和二级质谱的碎片离子，结合参考谱图和软件数据库检索及相关文献报道，对浙贝母不同部位的差异指标成分进行了鉴定和分析。结果：共鉴定出 20 种成分，其中块根中鉴定出 13 种，须根中鉴定出 7 种，叶片中鉴定出 8 种，并对其化合物的结构裂解进行了分析。结论为今后将鹤顶红全株用作药物提供了可能性和理论依据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Natural Product Communications

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