Depth dose measurement by using Al2O3 OSL dosimeters in high energy photons in the presence of air cavity and density inhomogeneity

Mohd Fahmi Mohd Yusof, Amirah Sauki, Nur Ateqah Suzaini, Arifah Nazirah Abdullah, Ahmad Bazlie Abd Kadir, Norriza Mohd Isa
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Abstract

Air cavities and tissue density inhomogeneity significantly affects the distribution of radiation doses, potentially resulting in adverse consequences such as cancer recurrence. This research aims to assess the accuracy of Al2O3 optically stimulated luminescence (OSL) dosimeters in measuring doses within varying thicknesses of air cavities (3, 5, and 8 cm) and tissue inhomogeneity of low and high density simulated by the lung and bone phantoms. An expanded polystyrene (EPS) was employed in homogeneous solid water® phantoms to simulate the air cavity. The percentage depth-dose (PDD) curves at 6 MV photons were obtained in both presence of air cavity and density inhomogeneity and compared to that in the EBT3 radiochromic film dosimeters and treatment planning system (TPS). The results indicated that the presence of an air cavity and tissue inhomogeneity affected the depth dose measured in OSL dosimeters, EBT3 films and TPS. OSLD and TPS showed good agreement at the centre of the cavity, which is within ±5% but could not estimate scattered radiation to the distal and proximal surfaces of the air cavity. The obtained p-values showed no significant differences of dose measured in OSL dosimeters compared to those in EBT3 films and TPS. The Kruskal Wallis test and Mann-Whitney showed no significant difference between OSL dosimeters, EBT3 film and TPS in the measurement of depth doses in the presence of density inhomogeneity. The overall results indicated the suitability of OSL dosimeters as indirect dosimeters for the measurements of depth dose in the presence of air cavity and tissue density inhomogeneity
在空气空腔和密度不均匀的情况下,使用 Al2O3 OSL 剂量计测量高能光子的深度剂量
气腔和组织密度的不均匀性会严重影响辐射剂量的分布,可能导致癌症复发等不良后果。本研究旨在评估 Al2O3 光激发发光(OSL)剂量计在不同厚度的气腔(3、5 和 8 厘米)内测量剂量的准确性,以及肺部和骨骼模型模拟的低密度和高密度组织不均匀性。在均质固体水®模型中使用了发泡聚苯乙烯(EPS)来模拟气腔。在存在气腔和密度不均匀的情况下,获得了 6 MV 光子下的深度剂量百分比(PDD)曲线,并与 EBT3 射线变色膜剂量计和治疗计划系统(TPS)中的曲线进行了比较。结果表明,气腔和组织不均匀性会影响 OSL 剂量计、EBT3 薄膜和 TPS 测得的深度剂量。OSLD 和 TPS 在气腔中心显示出良好的一致性,在 ±5% 的范围内,但无法估算气腔远端和近端表面的散射辐射。得出的 p 值显示,OSL 剂量计测量的剂量与 EBT3 胶片和 TPS 测量的剂量相比没有显著差异。Kruskal Wallis 检验和 Mann-Whitney 检验表明,在密度不均匀的情况下,OSL 剂量计、EBT3 薄膜和 TPS 在测量深度剂量方面没有明显差异。总体结果表明,OSL剂量计适合作为间接剂量计,在存在气腔和组织密度不均匀的情况下测量深度剂量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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