Anatomic Outcomes of Lens-Sparing Vitrectomy for Stage 3 or 4 Familial Exudative Vitreoretinopathy

Retina Pub Date : 2024-05-02 DOI:10.1097/iae.0000000000004147

Huanyu Liu, Wenting Zhang, Victoria Y. Gu, Xueru Zhang, Yuan Yang, Haodong Xiao, Jiawei Yin, Dian Jiao, Tian Tian, Jie Peng, Peiquan Zhao

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Abstract

To report the anatomic outcomes and retinal structure changes from lens-sparing vitrectomy (LSV) for eyes with Stage 3 or 4 familial exudative vitreoretinopathy (FEVR). We retrospectively reviewed 133 consecutive eyes of 119 patients with Stage 3 (51 eyes) or 4 (82 eyes) FEVR who underwent LSV between January 2012 to May 2023. 129 eyes (97.0%) achieved traction relief through one LSV operation. The extent of retinal detachment extent improved in 98 eyes (73.7%), remained stable in 32 eyes (24.1%), and progressed in 3 eyes (2.3%). At long-term follow-up, 39 (29.3%) and 60 (45.1%) eyes had completely or partially reattached retina, respectively. The median change of venular angle was 3.6° (95% CI, 3.5 to 10.5; P < 0.001) and -9.9° (95% CI, -15.8 to -4.6; P < 0.001) for temporal and nasal vessels. The mean disc-fovea distance was 0.3 papillary diameter shorter (95% CI, -0.4 to -0.2; P < 0.001) and mean temporal venular arcade distance was 0.02 papillary diameter larger (95% CI, -0.16 to 0.21; P = 0.361). These results suggest that LSV can relieve vitreoretinal traction and reattach the retina in late Stage FEVR eyes. Improvements in temporal and nasal venular angle, and disc-fovea distance reflect positive retinal structure changes for patients.

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家族性渗出性玻璃体视网膜病变 3 或 4 期保晶体玻璃体切除术的解剖结果

目的：报告对家族性渗出性玻璃体视网膜病变（FEVR）第 3 期或第 4 期患者行保晶状体玻璃体切除术（LSV）的解剖结果和视网膜结构变化。我们对 2012 年 1 月至 2023 年 5 月期间接受 LSV 的 119 名 FEVR 3 期（51 眼）或 4 期（82 眼）患者的 133 只连续眼进行了回顾性研究。 129只眼睛（97.0%）通过一次LSV手术缓解了牵引。98只眼睛（73.7%）的视网膜脱离程度有所改善，32只眼睛（24.1%）保持稳定，3只眼睛（2.3%）的视网膜脱离程度有所进展。在长期随访中，分别有 39 眼（29.3%）和 60 眼（45.1%）视网膜完全或部分重新附着。静脉角度变化的中位数为 3.6° (95% CI, 3.5 to 10.5; P < 0.001)，颞部和鼻部血管变化的中位数为 -9.9° (95% CI, -15.8 to -4.6; P < 0.001)。椎间盘-眼窝平均距离缩短了 0.3 个乳头直径（95% CI，-0.4 至 -0.2；P < 0.001），颞静脉弧平均距离增加了 0.02 个乳头直径（95% CI，-0.16 至 0.21；P = 0.361）。这些结果表明，LSV 可以缓解晚期 FEVR 眼睛的玻璃体视网膜牵引并重新连接视网膜。颞静脉角、鼻静脉角和视盘-眼窝距离的改善反映了患者视网膜结构的积极变化。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Retina

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