Prevalence of Asymptomatic Bacteriuria among Patients Attending Diabetic Clinic at Fort Port Regional Referral Hospital, Uganda Patients

Wardat Rashid Ali, Alina Peris, Stella Nabirye, Awil Abdi, Nihfadh Tamali, Venance Emmanuel, Dayyabu Shehu
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Abstract

The availability of high concentration of sugar in the blood of diabetic patients makes them more susceptible to developing bacterial infections which are asymptomatic commonly referred to as asymptomatic bacteriuria (ASB) than the non-diabetic patients. Diabetes patients with ASB have a much higher risk of developing diabetic complications than individuals without ASB. There is a paucity of data on the burden of ASB and antimicrobial susceptibility in diabetes patients in Uganda. Between March and May 2023, a cross-sectional study was carried out at the Fort Portal Regional Referral Hospital, Uganda outpatient diabetic clinic and 160 diabetes patients were recruited for the study. Mid-stream urine was taken for culture and sensitivity. Data analysis were performed using IBM SPSS version 20. A pie chart was used to display the prevalence and antimicrobial susceptibility patterns of common uropathogens described in frequency and percentages. The overall prevalence of ASB among the study participants was 11%. The most common uropathogen isolated was Escherichia coli, followed by Klebsiella and S. aureus. The most sensitive drug in all the isolates was Nitrofrantoin and resistant drug was Ampicillin. In conclusion, routine testing for ASB and treatment should be according to the antimicrobial susceptibility of diabetic patients.
乌干达港堡地区转诊医院糖尿病门诊患者无症状性细菌尿的患病率 患者
与非糖尿病患者相比,糖尿病患者血液中高浓度的糖分使他们更容易发生无症状的细菌感染,通常称为无症状菌尿(ASB)。与无症状菌尿的患者相比,有无症状菌尿的糖尿病患者发生糖尿病并发症的风险要高得多。有关乌干达糖尿病患者ASB负担和抗菌药物敏感性的数据很少。2023 年 3 月至 5 月期间,一项横断面研究在乌干达波特尔堡地区转诊医院的糖尿病门诊进行,共招募了 160 名糖尿病患者参与研究。采集中段尿液进行培养和药敏试验。数据分析使用 IBM SPSS 20 版本进行。采用饼图显示常见尿路病原体的流行率和抗菌药敏感性模式,以频率和百分比表示。在研究参与者中,ASB 的总体流行率为 11%。最常见的尿路病原体是大肠埃希菌,其次是克雷伯氏菌和金黄色葡萄球菌。所有分离菌中最敏感的药物是硝基呋喃妥因,耐药药物是氨苄西林。总之,应根据糖尿病患者对抗菌药的敏感性对 ASB 进行常规检测和治疗。
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