A Review on Pharmacological Advancement of Ellagic Acid

Pougang Golmei, Sweta Kasna, Kumar Probin Roy, Sachin Kumar
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Abstract

Background: In recent years, ellagic acid has emerged as a focal point in pharmacological research, showcasing promising developments and potential therapeutic applications as a competitive inhibitor of Src homology phosphotyrosyl phosphatase 2 for the treatment of cancer, as a shielding impact that stimulates sirtuin 6 (SIRT 6), against nephrotoxicity induced by cisplatin, as adjuvant treatment in sickle cell anemia, as antiaging and to avoid mild cognitive impairment. Purpose: This review provides a concise overview of the latest advancements in ellagic acid research, highlighting novel pharmacological findings and emerging trends. Methods: A comprehensive search of relevant literature was conducted to gather information on the pharmacological properties and therapeutic applications of ellagic acid. Studies investigating its antioxidant properties, anti-inflammatory effects, molecular interactions, and therapeutic implications were included in the analysis. Results: The review summarizes the multifaceted pharmacological landscape of ellagic acid, encompassing its antioxidant properties, anti-inflammatory effects, and potential therapeutic applications. It sheds light on its evolving role in modern medicine and underscores its significance as a promising avenue for future pharmaceutical exploration. Conclusion: The recent strides in ellagic acid development highlight its potential as a valuable therapeutic agent in various health conditions. Further research into its molecular interactions and clinical applications is warranted to fully harness its therapeutic potential and improve patient outcomes.
鞣花酸药理研究进展综述
背景:近年来,鞣花酸已成为药理学研究的一个焦点,它作为治疗癌症的 Src 同源膦酰基磷酸酶 2 的竞争性抑制剂、刺激 sirtuin 6 (SIRT 6) 的屏蔽作用、顺铂诱导的肾毒性、镰状细胞性贫血的辅助治疗、抗衰老和避免轻度认知障碍等,都展示了其广阔的发展前景和潜在的治疗应用。目的:这篇综述简明扼要地概述了鞣花酸研究的最新进展,重点介绍了新的药理学发现和新兴趋势。研究方法对相关文献进行了全面检索,以收集有关鞣花酸药理特性和治疗应用的信息。分析包括有关鞣花酸抗氧化特性、抗炎作用、分子相互作用和治疗意义的研究。结果:综述总结了鞣花酸的多方面药理作用,包括其抗氧化特性、抗炎作用和潜在的治疗应用。它揭示了鞣花酸在现代医学中不断发展的作用,并强调了鞣花酸作为未来药物探索的一个重要途径的意义。结论:鞣花酸的最新发展突显了它作为治疗各种健康状况的重要药物的潜力。为了充分利用鞣花酸的治疗潜力并改善患者的治疗效果,有必要对其分子相互作用和临床应用进行进一步研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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