Nephrotransplantectomy Using Radiosurgical Techniques

R. R. Akhtyamov, V. P. Ionin
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Abstract

Introduction. Aſter the loss of kidney transplant function, patient curation can be a difficult task. Nephrotransplantectomy (NTE) is the method of choice between reduction of immunosuppression with the abandonment of a non-functioning kidney transplant and embolization. This is an operation with potentially significant indicators of blood loss, complications and mortality. Along with traditional NTE, we began to use endovascular isolation of the allograſt as a method of preoperative preparation before its removal.The aim of the work is to investigate the effect of the use of radiosurgical minimally invasive techniques on the surgical tactics of nephrotransplantectomy, the degree of blood loss, the frequency of complications and blood transfusion.Materials and methods. A retrospective analysis of the data of 52 patients aſter NTE was performed. Depending on the method, patients are divided into two groups. In group 1 (main, n = 22), the operation was performed with pre-performed endovascular embolization of the graſt arteries (EEAT), in group 2 (control, n = 30) — without EEAT. The analysis of the results of the examination, intra- and postoperative indicators in patients by groups was carried out.Results. In group 1, intraoperative blood loss was 10–80 ml, on average (35.4±19.9) ml; in group 2 — from 100 to 600 ml, on average (289.7±138.4) ml (p < 0.001). In group 2, damage to the main vessels occurred more oſten (n = 4) (13.3 % vs. 0 %), hemotransfusion was performed in 53.3 % of cases (n = 16) to correct posthemorrhagic anemia. Postoperative complications in the control group were recorded in 8 patients (26.7 %).Discussion. Preventive endovascular embolization of the arteries of a kidney transplant significantly reduces the frequency ofintra- and postoperative complications, allows nephrectomy to be performed on a planned basis andin a delayed manner.
利用放射外科技术进行肾移植手术
导言。肾移植功能丧失后,病人的治疗是一项艰巨的任务。肾移植切除术(NTE)是在减少免疫抑制、放弃无功能肾移植和栓塞之间的一种选择。这种手术的失血量、并发症和死亡率指标可能非常高。除了传统的NTE外,我们还开始使用血管内分离异体肾脏的方法,作为切除异体肾脏前的术前准备。这项工作的目的是研究放射外科微创技术的使用对肾移植手术战术、失血量、并发症发生频率和输血的影响。对 52 例 NTE 患者的数据进行了回顾性分析。根据方法不同,患者分为两组。第 1 组(主要组,n = 22)在手术前进行了大动脉血管内栓塞(EEAT),第 2 组(对照组,n = 30)没有进行 EEAT。对各组患者的检查结果、术中和术后指标进行了分析。第 1 组患者术中失血量为 10-80 毫升,平均(35.4±19.9)毫升;第 2 组患者术中失血量为 100-600 毫升,平均(289.7±138.4)毫升(P < 0.001)。在第 2 组中,主血管损伤发生率更高(4 例)(13.3% 对 0%),53.3% 的病例(16 例)进行了输血以纠正出血性贫血。对照组有8名患者(26.7%)出现术后并发症。肾移植动脉的预防性血管内栓塞术显著降低了术中和术后并发症的发生率,使肾切除术可以有计划地延迟进行。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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