Perioperative Outcomes after Elective Laparoscopic Cholecystectomy in High Risk Patients

Fazal Ur Rehman, Mujahid Zulfiqar Ali, Maheen Zafar, Madeeha Ikram, Aqsa Tassadduq, Muhammad Farrukh Habib
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Abstract

Background: The global population is aging, leading to an increased incidence of acute cholecystitis and associated complications in the elderly. While laparoscopic cholecystectomy is the gold standard for treating acute cholecystitis, its safety and outcomes in high-risk, elderly patients with comorbidities are not well-documented. Objective: To compare postoperative complications, hospital stay duration, and nursing care requirements between high-risk elderly patients undergoing tube cholecystostomy versus early elective laparoscopic cholecystectomy for acute cholecystitis. Methods: This cross-sectional comparative study was conducted at Combined Military Hospital Rawalpindi from July 2021 to January 2022. A total of 70 patients aged 40-80 years and classified as ASA 3 or 4 were included. Patients were divided into two groups: Group 1 (n=35) underwent tube cholecystostomy followed by interval cholecystectomy after six weeks; Group 2 (n=35) underwent early elective laparoscopic cholecystectomy within 72 hours of admission. Data on hospital stay, postoperative complications, and nursing care were collected and analyzed using SPSS version 25.0. Quantitative data were presented as mean ± standard deviation (SD), and qualitative data as frequency and percentage. Independent t-tests were applied, with a p-value of less than 0.05 considered statistically significant. Results: In Group 1, 91% of patients had a hospital stay of less than 5 days compared to 11% in Group 2 (p=0.000). Group 1 had 94% of patients nursed in the ward/HDU, while 94% of Group 2 required ICU care (p=0.000). Postoperative complications were significantly lower in Group 1, with 97% having no complications compared to 34% in Group 2 (p=0.000). Only 3% of Group 1 required multidisciplinary team management versus 66% in Group 2. Conclusion: Tube cholecystostomy is a safer and more effective initial management strategy for high-risk elderly patients with acute cholecystitis, leading to shorter hospital stays, less intensive postoperative care, and fewer complications compared to early elective laparoscopic cholecystectomy.
高危患者选择性腹腔镜胆囊切除术的围手术期结果
背景:全球人口老龄化导致老年人急性胆囊炎及相关并发症的发病率增加。虽然腹腔镜胆囊切除术是治疗急性胆囊炎的金标准,但其在高风险、有合并症的老年患者中的安全性和疗效并没有得到充分证实:比较急性胆囊炎高危老年患者接受胆囊造口术与早期选择性腹腔镜胆囊切除术的术后并发症、住院时间和护理要求:这项横断面比较研究于 2021 年 7 月至 2022 年 1 月在拉瓦尔品第联合军事医院进行。共纳入了 70 名年龄在 40-80 岁之间、ASA 分级为 3 级或 4 级的患者。患者被分为两组:第一组(35 人)接受胆囊管造口术,六周后进行间歇性胆囊切除术;第二组(35 人)在入院 72 小时内接受早期选择性腹腔镜胆囊切除术。使用 SPSS 25.0 版收集和分析住院时间、术后并发症和护理数据。定量数据以均数±标准差(SD)表示,定性数据以频率和百分比表示。采用独立 t 检验,P 值小于 0.05 为差异有统计学意义:第一组有 91% 的患者住院时间少于 5 天,而第二组只有 11% 的患者住院时间少于 5 天(P=0.000)。第一组有 94% 的患者在病房/重症监护室接受护理,而第二组有 94% 的患者需要重症监护室护理(P=0.000)。第一组的术后并发症明显较少,97%的患者没有并发症,而第二组只有34%的患者没有并发症(P=0.000)。第一组只有3%的患者需要多学科团队管理,而第二组则为66%:与早期选择性腹腔镜胆囊切除术相比,置管胆囊造口术是高风险老年急性胆囊炎患者更安全、更有效的初始治疗策略,可缩短住院时间,减少术后护理强度,减少并发症。
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