B. Gopal, Prasoon Raj Singh, Shubham Bhatt, Avijit Goswami
{"title":"BF3·OEt2 Mediated (3+2) Cycloaddition Reactions of DACs with Cyanamides: Access to Cyclic Amidines","authors":"B. Gopal, Prasoon Raj Singh, Shubham Bhatt, Avijit Goswami","doi":"10.1055/a-2323-0721","DOIUrl":null,"url":null,"abstract":"A BF3·OEt2 promoted facile synthesis of cyclic amidines has been developed via the (3+2)-cycloaddition of cyanamides with donor-acceptor cyclopropanes (DACs). In addition to this, the protocol has been successfully extended to construct dimerized amidine derivative and gram-scale synthesis with great efficiency.","PeriodicalId":510101,"journal":{"name":"Synthesis","volume":"122 45","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Synthesis","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1055/a-2323-0721","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
A BF3·OEt2 promoted facile synthesis of cyclic amidines has been developed via the (3+2)-cycloaddition of cyanamides with donor-acceptor cyclopropanes (DACs). In addition to this, the protocol has been successfully extended to construct dimerized amidine derivative and gram-scale synthesis with great efficiency.