Anemia of chronic diseases

N. Orlova, N. D. Karseladze
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Abstract

Anemia of chronic diseases is one of the most common diseases and has a significant impact on prognosis and mortality. The article discusses the relevance, pathogenesis, clinical manifestations, laboratory diagnostics, and treatment of anemia of chronic diseases. The treatment of anemia depends on the severity and the disease of which it is a complication. Anemia is considered in oncological diseases, chronic kidney disease, chronic heart failure, cirrhosis of the liver, celiac disease, etc. Therapy aimed at replenishing iron deficiency includes transfusion of erythrocyte mass, erythropoietin stimulants, iron-containing drugs. According to the literature review, information is provided on the peculiarities of managing patients with anemia in various chronic diseases, an overview of the modern approach to ferrotherapy and its complications is given. Information is provided on a new form of oral iron – Sucrosomal iron (SiderAL Forte), which is well tolerated and has high bioavailability. A review of clinical studies confirming the efficacy and safety of oral Sucrosomal iron is presented.
慢性病贫血
慢性病贫血是最常见的疾病之一,对预后和死亡率有重大影响。本文讨论了慢性病贫血的相关性、发病机制、临床表现、实验室诊断和治疗。贫血的治疗取决于其严重程度和作为并发症的疾病。肿瘤疾病、慢性肾病、慢性心力衰竭、肝硬化、乳糜泻等都会出现贫血。旨在补充缺铁的疗法包括输注大量红细胞、促红细胞生成素、含铁药物。根据文献综述,提供了关于各种慢性疾病贫血患者的特殊治疗方法的信息,概述了现代铁治疗方法及其并发症。还介绍了一种新型口服铁剂--蔗糖铁(SiderAL Forte),这种铁剂具有良好的耐受性和高生物利用度。文章回顾了证实口服琥珀酰铁剂疗效和安全性的临床研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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