Diagnosis and treatment of oral mucus lesions: case series of four patients

N. P. Teplyuk, M. A. Stepanov, Mariya I. Dodina, B. Damdinova
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Abstract

One of the pressing issues in dermatovenerological and stomatological practices pertains to diseases of the oral mucosa. This challenge is primarily attributed to the intricacies associated with diagnosing these conditions in their early stages, the resemblance of clinical presentations to various oral mucosal lesions, and the potential lack of awareness among healthcare practitioners. Diseases such as lichen planus, herpes simplex, erythema multiforme exudative with skin lesions and vulgar pemphigus are characterized by a particularly persistent long-term course, thereby reducing the patient's ability to work and the overall quality of life. A multitude of endogenous and exogenous factors can influence the state of the oral mucosa. Endogenous factors encompass genetic predisposition, endocrine disturbances, carbohydrate metabolism disorders, neurogenic disorders, autoimmune conditions and infectious diseases. Exogenous factors, as a rule, include taking medications (non-steroidal anti-inflammatory drugs, antibiotics), galvanism, excessive use of alcohol and narcotic substances, and others. It should be noted that the condition of the oral mucosa is also influenced by a wide range of different trigger factors. The narrative delves into the complexities of diagnosing these conditions early on and explores the challenges inherent in devising effective treatment strategies.
口腔黏液病变的诊断和治疗:四名患者的病例系列
口腔黏膜疾病是皮肤退行性病学和口腔医学实践中亟待解决的问题之一。造成这一挑战的主要原因包括:在早期阶段诊断这些疾病的复杂性、临床表现与各种口腔黏膜病变的相似性,以及医疗从业人员可能缺乏相关意识。扁平苔藓、单纯疱疹、渗出性多形红斑、寻常型丘疹性荨麻疹等疾病的特点是长期病程特别持久,从而降低了患者的工作能力和整体生活质量。多种内源性和外源性因素都会影响口腔黏膜的状态。内源性因素包括遗传易感性、内分泌紊乱、碳水化合物代谢紊乱、神经源性紊乱、自身免疫性疾病和传染病。外源性因素通常包括服用药物(非甾体抗炎药、抗生素)、电击、过度饮酒和服用麻醉药物等。值得注意的是,口腔黏膜的状况也会受到各种不同诱发因素的影响。报告深入探讨了早期诊断这些病症的复杂性,并探讨了制定有效治疗策略的内在挑战。
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