A Review on Fast Dissolving Tablet

VS. Ughde, S. Deshmane, K. Biyani
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引用次数: 31

Abstract

Drug delivery systems play a crucial role in the effective administration of medications. Solid dosage forms, such as tablets and capsules, are widely accepted due to their ease of administration, accurate dosage, and patient compliance. However, the challenge lies in developing an ideal drug delivery system that ensures the right rate and concentration of drug delivery to achieve maximum therapeutic effect and minimal adverse effects. Fast dissolving tablets (FDTs) have emerged as an alternative to conventional dosage forms, especially for paediatric, geriatric, and uncooperative patients, as well as for situations where water is unavailable. The study aims to comprehensive review of the literature to analyse the advantages and disadvantages, patented technologies, formulation techniques, and properties of ideal FDTs. The review also examines the various formulation techniques, including freeze drying, tablet moulding, spray drying, sublimation, direct compression, and mass extrusion
速溶片剂综述
给药系统在有效给药方面发挥着至关重要的作用。片剂和胶囊等固体剂型因其给药方便、剂量准确、患者遵从等优点而被广泛接受。然而,如何开发一种理想的给药系统,确保合适的给药速度和浓度,以达到最大的治疗效果和最小的不良反应,却是一项挑战。快速溶解片剂(FDTs)已成为传统剂型的替代品,尤其适用于儿科、老年病和不合作的病人,以及无法用水的情况。本研究旨在对文献进行全面回顾,分析理想无菌滴剂的优缺点、专利技术、配制技术和特性。综述还研究了各种配制技术,包括冷冻干燥、片剂模塑、喷雾干燥、升华、直接压缩和大规模挤压。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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