Formulation and Evaluation of Logenzes for Anticoagulantion

Pawar Sanket Sambhaji, Gagare Sagar Devram, Waphare Sampada Thakaji, Gund Sanket Dhyandev, Mr. Agale Sir
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Abstract

Cardiovascular diseases represent a significant global health burden, necessitating effective prevention and treatment strategies to mitigate their impact. Anticoagulant therapy plays a crucial role in managing these diseases by preventing the formation of blood clots, which can lead to life-threatening complications such as heart attacks and strokes. However, conventional anticoagulants are associated with limitations, including the risk of bleeding complications and the need for frequent monitoring. In recent years, there has been increasing interest in exploring natural alternatives to conventional anticoagulants, with Cayenne pepper (Capsicum annuum) emerging as a potential candidate due to its bioactive compound, capsaicin. This paper aims to review the existing literature on the anticoagulant properties of Cayenne pepper lozenges. By examining the pharmacological mechanisms of capsaicin and summarizing preclinical and clinical studies, this paper evaluates the efficacy, safety, and therapeutic potential of Cayenne pepper as an alternative or adjunctive therapy for cardiovascular diseases. The findings suggest that Cayenne pepper lozenges may hold promise as a novel anticoagulant agent, offering potential benefits in terms of cardiovascular health and reducing the burden associated with conventional anticoagulant therapy
用于抗凝血的 Logenzes 的配制和评估
心血管疾病给全球健康带来沉重负担,因此需要有效的预防和治疗策略来减轻其影响。抗凝疗法在控制这些疾病方面发挥着至关重要的作用,它能防止血凝块的形成,而血凝块可导致心脏病发作和中风等危及生命的并发症。然而,传统的抗凝剂有其局限性,包括出血并发症的风险和需要频繁监测。近年来,人们对探索传统抗凝剂的天然替代品越来越感兴趣,辣椒(Capsicum annuum)因其生物活性化合物辣椒素而成为潜在的候选药物。本文旨在回顾有关卡宴辣椒锭抗凝特性的现有文献。通过研究辣椒素的药理机制并总结临床前和临床研究,本文评估了辣椒作为心血管疾病替代疗法或辅助疗法的有效性、安全性和治疗潜力。研究结果表明,辣椒素锭作为一种新型抗凝剂可能具有前景,可为心血管健康带来潜在益处,并减轻与传统抗凝剂疗法相关的负担。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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