Exploring the link between dietary omega-3 and omega-6 fatty acid intake and rheumatoid arthritis risk: NHANES 1999-2020 study.

IF 3.4 4区医学 Q2 RHEUMATOLOGY

Clinical and experimental rheumatology Pub Date : 2024-09-01 Epub Date: 2024-05-06 DOI:10.55563/clinexprheumatol/91tmfb

Tianlun Kang, Yajing Xi, Tangliang Qian, Siyi Lu, Mengmeng Du, Xiaojun Shi, Xiujuan Hou

{"title":"Exploring the link between dietary omega-3 and omega-6 fatty acid intake and rheumatoid arthritis risk: NHANES 1999-2020 study.","authors":"Tianlun Kang, Yajing Xi, Tangliang Qian, Siyi Lu, Mengmeng Du, Xiaojun Shi, Xiujuan Hou","doi":"10.55563/clinexprheumatol/91tmfb","DOIUrl":null,"url":null,"abstract":"Objectives: The association between the ingestion of n-3 and n-6 fatty acids and rheumatoid arthritis (RA) remains unclear. To address this, this study utilised data from the National Health and Nutrition Examination Survey (NHANES) spanning from 1999 to 2020.Methods: Dietary intake information on n-3 and n-6 fatty acids was gathered through 24-hour interviews about dietary recall and adjusted based on weight. RA patient data was collected using questionnaires. Associations were evaluated using logistic regression and spline analyses. The study included a total of 50,352 participants in a cross-sectional manner.Results: In the adjusted Model 2, higher odds ratios (ORs) of 0.72 (95% CI: 0.60-0.86) and 0.76 (95% CI: 0.62-0.92) were observed for n-3 and n-6 fatty acid intake, respectively, compared to the lowest category.Conclusions: The results suggest a negative correlation between the ingestion of n-3 and n-6 fatty acids and the risk of rheumatoid arthritis in US adults.","PeriodicalId":10274,"journal":{"name":"Clinical and experimental rheumatology","volume":" ","pages":"1720-1728"},"PeriodicalIF":3.4000,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical and experimental rheumatology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.55563/clinexprheumatol/91tmfb","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/5/6 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"RHEUMATOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Objectives: The association between the ingestion of n-3 and n-6 fatty acids and rheumatoid arthritis (RA) remains unclear. To address this, this study utilised data from the National Health and Nutrition Examination Survey (NHANES) spanning from 1999 to 2020.

Methods: Dietary intake information on n-3 and n-6 fatty acids was gathered through 24-hour interviews about dietary recall and adjusted based on weight. RA patient data was collected using questionnaires. Associations were evaluated using logistic regression and spline analyses. The study included a total of 50,352 participants in a cross-sectional manner.

Results: In the adjusted Model 2, higher odds ratios (ORs) of 0.72 (95% CI: 0.60-0.86) and 0.76 (95% CI: 0.62-0.92) were observed for n-3 and n-6 fatty acid intake, respectively, compared to the lowest category.

Conclusions: The results suggest a negative correlation between the ingestion of n-3 and n-6 fatty acids and the risk of rheumatoid arthritis in US adults.

查看原文本刊更多论文

探索膳食中欧米茄-3 和欧米茄-6 脂肪酸摄入量与类风湿性关节炎风险之间的联系：NHANES 1999-2020 研究。

目的：n-3和n-6脂肪酸的摄入与类风湿性关节炎（RA）之间的关系仍不清楚。为解决这一问题，本研究利用了1999年至2020年期间美国国家健康与营养调查（NHANES）的数据：n-3和n-6脂肪酸的膳食摄入量信息是通过24小时膳食回忆访谈收集的，并根据体重进行了调整。通过问卷调查收集 RA 患者数据。采用逻辑回归和样条分析法对相关性进行评估。研究共纳入了 50,352 名横断面参与者：在调整后的模型 2 中，与最低类别相比，n-3 和 n-6 脂肪酸摄入量的几率比（ORs）分别为 0.72（95% CI：0.60-0.86）和 0.76（95% CI：0.62-0.92）：结论：研究结果表明，在美国成年人中，n-3 和 n-6 脂肪酸的摄入量与类风湿性关节炎的发病风险呈负相关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Clinical and experimental rheumatology 医学-风湿病学

CiteScore

6.10

自引率

18.90%

发文量

377

审稿时长

3-6 weeks

期刊介绍： Clinical and Experimental Rheumatology is a bi-monthly international peer-reviewed journal which has been covering all clinical, experimental and translational aspects of musculoskeletal, arthritic and connective tissue diseases since 1983.