Human Pose Estimation for Clinical Analysis of Gait Pathologies.

IF 2.3 Q3 BIOCHEMICAL RESEARCH METHODS
Bioinformatics and Biology Insights Pub Date : 2024-05-15 eCollection Date: 2024-01-01 DOI:10.1177/11779322241231108
Manal Mostafa Ali, Maha Medhat Hassan, M Zaki
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引用次数: 0

Abstract

Gait analysis serves as a critical diagnostic tool for identifying neurologic and musculoskeletal damage. Traditional manual analysis of motion data, however, is labor-intensive and heavily reliant on the expertise and judgment of the therapist. This study introduces a binary classification method for the quantitative assessment of gait impairments, specifically focusing on Duchenne muscular dystrophy (DMD), a prevalent and fatal neuromuscular genetic disorder. The research compares spatiotemporal and sagittal kinematic gait features derived from 2D and 3D human pose estimation trajectories against concurrently recorded 3D motion capture (MoCap) data from healthy children. The proposed model leverages a novel benchmark dataset, collected from YouTube and publicly available datasets of their typically developed peers, to extract time-distance variables (e.g. speed, step length, stride time, and cadence) and sagittal joint angles of the lower extremity (e.g. hip, knee, and knee flexion angles). Machine learning and deep learning techniques are employed to discern patterns that can identify children exhibiting DMD gait disturbances. While the current model is capable of distinguishing between healthy subjects and those with DMD, it does not specifically differentiate between DMD patients and patients with other gait impairments. Experimental results validate the efficacy of our cost-effective method, which relies on recorded RGB video, in detecting gait abnormalities, achieving a prediction accuracy of 96.2% for Support Vector Machine (SVM) and 97% for the deep network.

用于步态病症临床分析的人体姿势估计。
步态分析是识别神经和肌肉骨骼损伤的重要诊断工具。然而,传统的手动运动数据分析耗费大量人力,而且严重依赖治疗师的专业知识和判断。本研究介绍了一种二元分类方法,用于对步态障碍进行定量评估,尤其侧重于杜氏肌营养不良症(DMD),这是一种普遍存在的致命性神经肌肉遗传疾病。该研究将从二维和三维人体姿势估计轨迹中得出的时空和矢状运动步态特征与同时记录的健康儿童三维运动捕捉(MoCap)数据进行了比较。拟议模型利用从 YouTube 和公开可用的典型同龄人数据集收集的新型基准数据集,提取时间-距离变量(如速度、步长、步幅时间和步频)和下肢矢状关节角度(如髋关节、膝关节和膝关节屈曲角度)。利用机器学习和深度学习技术,可以识别出表现出 DMD 步态障碍的儿童的模式。虽然目前的模型能够区分健康受试者和 DMD 患者,但并不能具体区分 DMD 患者和其他步态障碍患者。实验结果验证了我们这种依靠录制的 RGB 视频检测步态异常的高性价比方法的有效性,支持向量机 (SVM) 的预测准确率达到 96.2%,深度网络的预测准确率达到 97%。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Bioinformatics and Biology Insights
Bioinformatics and Biology Insights BIOCHEMICAL RESEARCH METHODS-
CiteScore
6.80
自引率
1.70%
发文量
36
审稿时长
8 weeks
期刊介绍: Bioinformatics and Biology Insights is an open access, peer-reviewed journal that considers articles on bioinformatics methods and their applications which must pertain to biological insights. All papers should be easily amenable to biologists and as such help bridge the gap between theories and applications.
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