{"title":"[The Role of the Anaesthesiologist in Liver Transplantation - Preoperative Evaluation].","authors":"Markus Müller, Christian Grasshoff","doi":"10.1055/a-2152-7350","DOIUrl":null,"url":null,"abstract":"<p><p>Preoperative evaluation prior to listing for orthotopic liver transplantation (LT) requires a careful multidisciplinary approach with specialized teams including surgeons, hepatologists and anesthesiologists in order to improve short- and long-term clinical outcomes. Due to inadequate supply of donor organs and changing demographics, patients listed for LT have become older, sicker and share more comorbidities. As cardiovascular events are the leading cause for early mortality precise evaluation of risk factors is mandatory. This review focuses on the detection and management of coronary artery disease, cirrhotic cardiomyopathy, portopulmonary hypertension and hepatopulmonary syndrome in patients awaiting LT. Further insights are being given into scoring systems, patients with Acute-on-chronic-liver-failure (ACLF), frailty, NASH cirrhosis and into psychologic evaluation of patients with substance abuse.</p>","PeriodicalId":7789,"journal":{"name":"Anasthesiologie Intensivmedizin Notfallmedizin Schmerztherapie","volume":"59 5","pages":"283-295"},"PeriodicalIF":0.3000,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Anasthesiologie Intensivmedizin Notfallmedizin Schmerztherapie","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1055/a-2152-7350","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/5/17 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"ANESTHESIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Preoperative evaluation prior to listing for orthotopic liver transplantation (LT) requires a careful multidisciplinary approach with specialized teams including surgeons, hepatologists and anesthesiologists in order to improve short- and long-term clinical outcomes. Due to inadequate supply of donor organs and changing demographics, patients listed for LT have become older, sicker and share more comorbidities. As cardiovascular events are the leading cause for early mortality precise evaluation of risk factors is mandatory. This review focuses on the detection and management of coronary artery disease, cirrhotic cardiomyopathy, portopulmonary hypertension and hepatopulmonary syndrome in patients awaiting LT. Further insights are being given into scoring systems, patients with Acute-on-chronic-liver-failure (ACLF), frailty, NASH cirrhosis and into psychologic evaluation of patients with substance abuse.
期刊介绍:
AINS ist die Fachzeitschrift für Anästhesiologie, Intensivmedizin, Notfallmedizin und Schmerztherapie im Georg Thieme Verlag. Sie vermittelt aktuelles Fachwissen und bietet Fortbildung. AINS hat sich das Ziel gesteckt, den Leserinnen und Lesern – Fachärzten und Weiterbildungsassistenten in der Anästhesiologie – immer praxisbezogenen Nutzwert und größtmögliche Unterstützung zu bieten.