[Contact allergy to the antifungal agent naftifin].

Abstract

Two patients treated topically against dermatophytes with a naftifine containing antifungal became allergic to the efficacious component naftifine. One of them also reacted to benzyl alcohol. Sensitization experiments in guinea pigs corroborated the suspicion that this allylamine is a contact sensitizer. To date, only few cases of allergic reactions to naftifine have been reported.