{"title":"Targeting Therapeutic Windows for Rheumatoid Arthritis Prevention.","authors":"Kai-Xin Gao, Yi-Hong Yang, Qi Liang, Li-Yan Mei, You-Bang Liang, Mao-Jie Wang, Xiu-Min Chen, Qing-Chun Huang, Ze-Huai Wen, Run-Yue Huang","doi":"10.1007/s11655-024-3760-2","DOIUrl":null,"url":null,"abstract":"<p><p>Rheumatoid arthritis (RA) is a worldwide public health problem. Interventions to delay or prevent the onset of RA have attracted much attention in recent years, and researchers are now exploring various prevention strategies. At present, there is still no unified consensus for RA prevention, but targeting therapeutic windows and implementing interventions for at-risk individuals are extremely important. Due to the limited number of clinical trials on pharmacologic interventions, further studies are needed to explore and establish optimal intervention regimens and effective measures to prevent progression to RA. In this review, we introduce the RA disease process and risk factors, and present research on the use of both Western and Chinese medicine from clinical perspectives regarding RA prevention. Furthermore, we describe several complete and ongoing clinical studies on the use of Chinese herbal formulae for the prevention of RA.</p>","PeriodicalId":10005,"journal":{"name":"Chinese Journal of Integrative Medicine","volume":" ","pages":"842-851"},"PeriodicalIF":2.2000,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chinese Journal of Integrative Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s11655-024-3760-2","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/5/16 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"INTEGRATIVE & COMPLEMENTARY MEDICINE","Score":null,"Total":0}
引用次数: 0
Abstract
Rheumatoid arthritis (RA) is a worldwide public health problem. Interventions to delay or prevent the onset of RA have attracted much attention in recent years, and researchers are now exploring various prevention strategies. At present, there is still no unified consensus for RA prevention, but targeting therapeutic windows and implementing interventions for at-risk individuals are extremely important. Due to the limited number of clinical trials on pharmacologic interventions, further studies are needed to explore and establish optimal intervention regimens and effective measures to prevent progression to RA. In this review, we introduce the RA disease process and risk factors, and present research on the use of both Western and Chinese medicine from clinical perspectives regarding RA prevention. Furthermore, we describe several complete and ongoing clinical studies on the use of Chinese herbal formulae for the prevention of RA.
类风湿性关节炎（RA）是一个全球性的公共卫生问题。近年来，延缓或预防类风湿关节炎发病的干预措施备受关注，研究人员正在探索各种预防策略。目前，关于 RA 的预防仍未达成统一共识，但针对治疗窗口期和高危人群实施干预措施极为重要。由于药物干预的临床试验数量有限，因此还需要进一步的研究来探索和确定最佳干预方案和有效措施，以预防RA的进展。在这篇综述中，我们介绍了 RA 的发病过程和风险因素，并从临床角度介绍了使用中西医预防 RA 的研究。此外，我们还介绍了几项关于使用中药配方预防RA的完整的和正在进行的临床研究。
期刊介绍：
Chinese Journal of Integrative Medicine seeks to promote international communication and exchange on integrative medicine as well as complementary and alternative medicine (CAM) and provide a rapid forum for the dissemination of scientific articles focusing on the latest developments and trends as well as experiences and achievements on integrative medicine or CAM in clinical practice, scientific research, education and healthcare.
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