Gafchromic EBT3 film provides equivalent dosimetric performance to EBT-XD film for stereotactic radiosurgery dosimetry.

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS
ACS Applied Bio Materials Pub Date : 2024-09-01 Epub Date: 2024-05-13 DOI:10.1007/s13246-024-01430-z
Lloyd Smyth, Andrew Alves, Katherine Collins, Sabeena Beveridge
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Abstract

The accurate assessment of film results is highly dependent on the methodology and techniques used to process film. This study aims to compare the performance of EBT3 and EBT-XD film for SRS dosimetry using two different film processing methods. Experiments were performed in a solid water slab and an anthropomorphic head phantom. For each experiment, the net optical density of the film was calculated using two different methods; taking the background (initial) optical density from 1) an unirradiated film from the same film lot as the irradiated film (stock to stock (S-S) method), and 2) a scan of the same piece of film taken prior to irradiation (film to film (F-F) method). EBT3 and EBT-XD performed similarly across the suite of experiments when using the green channel only or with triple channel RGB dosimetry. The dosimetric performance of EBT-XD was improved across all colour channels by using an F-F method, particularly for the blue channel. In contrast, EBT3 performed similarly well regardless of the net optical density method used. Across 21 SRS treatment plans, the average per-pixel agreement between EBT3 and EBT-XD films, normalised to the 20 Gy prescription dose, was within 2% and 4% for the non-target (2-10 Gy) and target (> 10 Gy) regions, respectively, when using the F-F method. At doses relevant to SRS, EBT3 provides comparable dosimetric performance to EBT-XD. In addition, an S-S dosimetry method is suitable for EBT3 while an F-F method should be adopted if using EBT-XD.

Abstract Image

Gafchromic EBT3 薄膜在立体定向放射手术剂量测定方面的剂量测定性能与 EBT-XD 薄膜相当。
胶片结果的准确评估在很大程度上取决于胶片处理的方法和技术。本研究旨在比较 EBT3 和 EBT-XD 胶片在 SRS 剂量测定中使用两种不同胶片处理方法的性能。实验在固体水板和拟人头部模型中进行。每次实验都使用两种不同的方法计算胶片的净光密度:1)来自与辐照胶片相同批次的未辐照胶片(库存到库存(S-S)方法);2)辐照前对同一块胶片的扫描(胶片到胶片(F-F)方法)。在仅使用绿色通道或三通道 RGB 剂量测定时,EBT3 和 EBT-XD 在整套实验中的表现相似。通过使用 F-F 方法,EBT-XD 在所有颜色通道的剂量测定性能都有所提高,尤其是在蓝色通道。相比之下,无论使用哪种净光密度方法,EBT3 的表现都差不多。在 21 个 SRS 治疗计划中,当使用 F-F 方法时,EBT3 和 EBT-XD 胶片(以 20 Gy 处方剂量为标准)在非靶区(2-10 Gy)和靶区(> 10 Gy)的平均每像素一致性分别在 2% 和 4% 以内。在 SRS 的相关剂量下,EBT3 的剂量学性能与 EBT-XD 相当。此外,S-S 剂量测定方法适用于 EBT3,而如果使用 EBT-XD 则应采用 F-F 方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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