Feasibility study of the application of magnetic resonance elastography (MRE) to measure oral posture related changes in stiffness of zygomaticus major muscle

IF 2.1 4区 医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Emi Hojo , Kevin J. Glaser , Ayako Harada-Hayashi , Yuan Le , Jun Chen , Thomas C. Hulshizer , Phillip J. Rossman , Sachiko Noyori , Neil Roberts
{"title":"Feasibility study of the application of magnetic resonance elastography (MRE) to measure oral posture related changes in stiffness of zygomaticus major muscle","authors":"Emi Hojo ,&nbsp;Kevin J. Glaser ,&nbsp;Ayako Harada-Hayashi ,&nbsp;Yuan Le ,&nbsp;Jun Chen ,&nbsp;Thomas C. Hulshizer ,&nbsp;Phillip J. Rossman ,&nbsp;Sachiko Noyori ,&nbsp;Neil Roberts","doi":"10.1016/j.mri.2024.05.005","DOIUrl":null,"url":null,"abstract":"<div><h3>Purpose</h3><p>Development of a technique for measuring the mechanical properties of zygomaticus major (ZM) may aid advances in clinical treatments for correcting abnormal oral posture. The objective of this work was to demonstrate the feasibility of measuring the stiffness of ZM using an MR elastography technique that incorporates a custom local driver and a phase-gradient (PG) inversion.</p></div><div><h3>Methods</h3><p>2D MRE investigations were performed for 3 healthy subjects using a vibration frequency of 90 Hz to test the prediction that the stiffness of ZM would be greater in the mouth-open compared to the mouth-closed position. MRE wave images were acquired along the long axis of ZM and processed using a 2D spatial-temporal directional filter applied in the direction of wave propagation along the long axis of the muscle. Stiffness measurements were obtained by applying the PG technique to a 1D-profile drawn in the phase image of the first harmonic of the wave images and a one-tailed paired <em>t</em>-test was used to compare the ZM stiffness between the two mouth postures (<em>p</em> &lt; 0.05).</p></div><div><h3>Results</h3><p>The mean stiffness and standard deviation (SD) of ZM across the three participants in the mouth-closed and mouth-open postures was 6.75 kPa (SD 3.36 kPa) and 15.5 kPa (SD 5.15 kPa), respectively. Changes of ZM stiffness were significantly greater in the mouth-open than the mouth-closed posture (<em>p</em> = 0.038).</p></div><div><h3>Conclusion</h3><p>The feasibility of using the PG MRE technique to measure stiffness changes in a small muscle such as ZM for different mouth postures has been demonstrated. Further investigations are required in a larger cohort of participants to investigate the sensitivity and reproducibility of the technique for potential clinical application as well as in health and beauty related studies.</p></div>","PeriodicalId":18165,"journal":{"name":"Magnetic resonance imaging","volume":"111 ","pages":"Pages 196-201"},"PeriodicalIF":2.1000,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0730725X24001541/pdfft?md5=7df358580028b1ffbb3b9be52efe586b&pid=1-s2.0-S0730725X24001541-main.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Magnetic resonance imaging","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0730725X24001541","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 0

Abstract

Purpose

Development of a technique for measuring the mechanical properties of zygomaticus major (ZM) may aid advances in clinical treatments for correcting abnormal oral posture. The objective of this work was to demonstrate the feasibility of measuring the stiffness of ZM using an MR elastography technique that incorporates a custom local driver and a phase-gradient (PG) inversion.

Methods

2D MRE investigations were performed for 3 healthy subjects using a vibration frequency of 90 Hz to test the prediction that the stiffness of ZM would be greater in the mouth-open compared to the mouth-closed position. MRE wave images were acquired along the long axis of ZM and processed using a 2D spatial-temporal directional filter applied in the direction of wave propagation along the long axis of the muscle. Stiffness measurements were obtained by applying the PG technique to a 1D-profile drawn in the phase image of the first harmonic of the wave images and a one-tailed paired t-test was used to compare the ZM stiffness between the two mouth postures (p < 0.05).

Results

The mean stiffness and standard deviation (SD) of ZM across the three participants in the mouth-closed and mouth-open postures was 6.75 kPa (SD 3.36 kPa) and 15.5 kPa (SD 5.15 kPa), respectively. Changes of ZM stiffness were significantly greater in the mouth-open than the mouth-closed posture (p = 0.038).

Conclusion

The feasibility of using the PG MRE technique to measure stiffness changes in a small muscle such as ZM for different mouth postures has been demonstrated. Further investigations are required in a larger cohort of participants to investigate the sensitivity and reproducibility of the technique for potential clinical application as well as in health and beauty related studies.

应用磁共振弹性成像(MRE)测量与口腔姿势相关的颧大肌硬度变化的可行性研究。
目的:开发一种测量颧骨大肌(ZM)机械特性的技术可能有助于临床治疗异常口腔姿势的进步。这项工作的目的是证明使用磁共振弹性成像技术测量颧大肌刚度的可行性,该技术结合了定制的局部驱动器和相梯度(PG)反转。方法:使用 90 Hz 的振动频率对 3 名健康受试者进行了二维 MRE 研究,以测试颧大肌刚度在张口位置比闭口位置更大的预测。MRE 波图像沿 ZM 长轴采集,并使用沿肌肉长轴波传播方向应用的二维时空方向滤波器进行处理。应用 PG 技术在波图像的第一次谐波相位图像中绘制一维轮廓,从而获得僵硬度测量结果,并使用单尾配对 t 检验比较每位参与者两种口腔姿势之间的 ZM 僵硬度(p 结果):三位参与者在闭口和张口姿势下的 ZM 平均硬度和标准差(SD)分别为 6.75 kPa(SD 3.36 kPa)和 15.5 kPa(SD 5.15 kPa)。张口姿势的 ZM 硬度变化明显大于闭口姿势(P = 0.038):使用 PG MRE 技术测量 ZM 等小肌肉在不同口腔姿势下的僵硬度变化的可行性已得到证实。还需要在更大的参与者群体中进行进一步调查,以研究该技术在潜在临床应用以及健康和美容相关研究中的灵敏度和可重复性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Magnetic resonance imaging
Magnetic resonance imaging 医学-核医学
CiteScore
4.70
自引率
4.00%
发文量
194
审稿时长
83 days
期刊介绍: Magnetic Resonance Imaging (MRI) is the first international multidisciplinary journal encompassing physical, life, and clinical science investigations as they relate to the development and use of magnetic resonance imaging. MRI is dedicated to both basic research, technological innovation and applications, providing a single forum for communication among radiologists, physicists, chemists, biochemists, biologists, engineers, internists, pathologists, physiologists, computer scientists, and mathematicians.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信