[Correlation between transcutaneous bilirubinometry and serum bilirubin in newborns ≥ 35 weeks].

IF 0.5 Q4 PEDIATRICS
Arantxa Vidal Esteban, Inmaculada Concepción Becerra Fernández, María José Rivero Martin
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引用次数: 0

Abstract

Clinical control and monitoring of bilirubin in the neonatal stage are essential to avoid toxicity in the central nervous system.

Objective: to determine the correlation between transcutaneous bilirubin (TcB) and total serum bilirubin (TSB) levels in newborns ≥ 35 weeks.

Patients and method: observational, cross-sectional, analytical, retrospective study that included 90 neonates of gestational age ≥ 35 weeks with mucocutaneous jaundice who underwent TcB and TSB measurement simultaneously between June 1, 2022, and January 31, 2023. Both variables were compared, determining their correlation.

Results: the validity indicators were analyzed, obtaining 100% sensitivity and negative predictive value. The mean of TcB determinations was 14.84 mg/dl ± 2.27 and that of TSB was 13.1 mg/dl ± 2.39. The correlation obtained indicates that both variables are related, which is a direct correlation and, according to the prediction equation, there is an appropriate correlation between them. It was determined that TcB overestimated TSB in 95.56% of the determinations, and underestimated TSB in the rest (4.44%). Simultaneous measurements of TcB and TSB were different in all determinations with a mean difference of 1.72 ± 1.48.

Conclusions: the non-invasive TcB method can be used as an initial screening tool for the neonatal population ≥ 35 weeks, given its adequate sensitivity and negative predictive value.

[≥35周新生儿经皮胆红素测定法与血清胆红素之间的相关性]。
新生儿期胆红素的临床控制和监测对于避免中枢神经系统中毒至关重要。目的:确定胎龄≥35 周新生儿经皮胆红素(TcB)和血清总胆红素(TSB)水平之间的相关性。患者和方法:观察性、横断面、分析性、回顾性研究,包括 90 名胎龄≥ 35 周的粘膜黄疸新生儿,他们在 2022 年 6 月 1 日至 2023 年 1 月 31 日期间同时接受了 TcB 和 TSB 测量。对这两个变量进行了比较,确定了它们之间的相关性。结果:对有效性指标进行了分析,灵敏度和阴性预测值均为 100%。TcB测定值的平均值为14.84 mg/dl ± 2.27,TSB测定值的平均值为13.1 mg/dl ± 2.39。所获得的相关性表明,这两个变量是相关的,是直接相关的,而且根据预测方程,它们之间存在适当的相关性。经测定,在 95.56% 的测定结果中,TcB 高估了 TSB,其余(4.44%)低估了 TSB。结论:无创 TcB 方法具有足够的灵敏度和阴性预测值,可用作≥ 35 周新生儿的初步筛查工具。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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