Deep Learning System for Left Ventricular Assist Device Candidate Assessment from Electrocardiograms.

Abstract

Left Ventricular Assist Devices (LVADs) are increasingly used as long-term implantation therapy for advanced heart failure patients, where candidacy assessment is crucial for successful treatment and recovery. A Deep Learning system based on Electrocardiogram (ECG) diagnoses criteria to stratify candidacy is proposed, implementing multi-model processing, interpretability, and uncertainty estimation. The approach includes beat segmentation for single-lead classification, 12-lead analysis, and semantic segmentation, achieving state-of-the-art results on the classification evaluation of each model, with multilabel average AUC results of 0.9924, 0.9468, and 0.9956, respectively, presenting a novel approach for LVAD candidacy assessment, serving as an aid for decision-making.