Perioperative pain optimization in the age of the opioid epidemic.

IF 2.3 3区 医学 Q2 ANESTHESIOLOGY
Current Opinion in Anesthesiology Pub Date : 2024-06-01 Epub Date: 2024-03-12 DOI:10.1097/ACO.0000000000001370
Janki Patel, Kyle Snyder, Amber K Brooks
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引用次数: 0

Abstract

Purpose of review: The opioid epidemic remains a constant and increasing threat to our society with overdoses and overdose deaths rising significantly during the COVID-19 pandemic. Growing evidence suggests a link between perioperative opioid use, postoperative opioid prescribing, and the development of opioid use disorder (OUD). As a result, strategies to better optimize pain management during the perioperative period are urgently needed. The purpose of this review is to summarize the most recent multimodal analgesia (MMA) recommendations, summarize evidence for efficacy surrounding the increased utilization of Enhanced Recovery After Surgery (ERAS) protocols, and discuss the implications for rising use of buprenorphine for OUD patients who present for surgery. In addition, this review will explore opportunities to expand our treatment of complex patients via transitional pain services.

Recent findings: There is ample evidence to support the benefits of MMA. However, optimal drug combinations remain understudied, presenting a target area for future research. ERAS protocols provide a more systematic and targeted approach for implementing MMA. ERAS protocols also allow for a more comprehensive approach to perioperative pain management by necessitating the involvement of surgical specialists. Increasingly, OUD patients taking buprenorphine are presenting for surgery. Recent guidance from a multisociety OUD working group recommends that buprenorphine not be routinely discontinued or tapered perioperatively. Lastly, there is emerging evidence to justify the use of transitional pain services for more comprehensive treatment of complex patients, like those with chronic pain, preoperative opioid tolerance, or substance use disorder.

Summary: Perioperative physicians must be aware of the impact of the opioid epidemic and explore methods like MMA techniques, ERAS protocols, and transitional pain services to improve the perioperative pain experience and decrease the risks of opioid-related harm.

阿片类药物流行时代的围手术期疼痛优化。
审查目的:在 COVID-19 大流行期间,阿片类药物的过量使用和过量死亡人数大幅上升,阿片类药物的流行对我们的社会构成了持续且日益严重的威胁。越来越多的证据表明,围手术期阿片类药物的使用、术后阿片类药物的处方以及阿片类药物使用障碍(OUD)的发生之间存在联系。因此,亟需制定策略来更好地优化围手术期的疼痛管理。本综述旨在总结最新的多模式镇痛(MMA)建议,总结围绕术后恢复强化方案(ERAS)使用增加的疗效证据,并讨论对接受手术的 OUD 患者使用丁丙诺啡增加的影响。此外,本综述还将探讨通过过渡性疼痛服务扩大对复杂患者治疗的机会:有大量证据支持 MMA 的益处。然而,对最佳药物组合的研究仍然不足,这也是未来研究的一个目标领域。ERAS 方案为实施 MMA 提供了一种更系统、更有针对性的方法。ERAS 方案还允许采用更全面的围手术期疼痛管理方法,因为它需要外科专家的参与。越来越多服用丁丙诺啡的 OUD 患者前来接受手术。多学会 OUD 工作组最近提出的指南建议,围手术期不要常规停用或减量丁丙诺啡。总结:围手术期医生必须意识到阿片类药物流行的影响,并探索 MMA 技术、ERAS 方案和过渡性疼痛服务等方法,以改善围手术期疼痛体验并降低阿片类药物相关伤害的风险。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
4.90
自引率
8.00%
发文量
207
审稿时长
12 months
期刊介绍: ​​​​​​​​Published bimonthly and offering a unique and wide ranging perspective on the key developments in the field, each issue of Current Opinion in Anesthesiology features hand-picked review articles from our team of expert editors. With fifteen disciplines published across the year – including cardiovascular anesthesiology, neuroanesthesia and pain medicine – every issue also contains annotated references detailing the merits of the most important papers.
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